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Melioidosis is an infectious disease caused by a gram-negative bacterium called Burkholderia pseudomallei. [1] Most people exposed to B. pseudomallei experience no symptoms; however, those who do experience symptoms have signs and symptoms that range from mild, such as fever and skin changes, to severe with pneumonia, abscesses, and septic shock that could cause death. [1]
The CDC has detected the deadly bacteria that causes melioidosis, aka Whitmore's Disease, in the U.S. for the first time. Here’s what to know.
White dot syndromes are inflammatory diseases characterized by the presence of white dots on the fundus, the interior surface of the eye. [1] The majority of individuals affected with white dot syndromes are younger than fifty years of age. Some symptoms include blurred vision and visual field loss. [2]
Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is an acquired inflammatory uveitis that belongs to the heterogenous group of white dot syndromes in which light-coloured (yellowish-white) lesions begin to form in the macular area of the retina.
An ocular manifestation of a systemic disease is an eye condition that directly or indirectly results from a disease process in another part of the body. There are many diseases known to cause ocular or visual changes.
Ashdown's medium is a selective culture medium for the isolation and characterisation of Burkholderia pseudomallei (the bacterium that causes melioidosis). Ashdown's medium was first described by LR Ashdown in 1979. [ 1 ]
A review of treatments showed that the anti-mite drug ivermectin can be an effective treatment for reducing symptoms. [24] Eye drops or ointments containing corticosteroids are frequently used in conjunction with antibiotics and can reduce eyelid inflammation. [4] [5] [25] The supplement n-acetylcysteine may be effective for blepharitis. [26]
Meibomian gland dysfunction is more often seen in women and is regarded as the main cause of dry eye disease. [14] [15] Factors that contribute to meibomian gland dysfunction can include things such as a person's age and/or hormones, [16] or severe infestation of Demodex brevis mite.