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The cell survival curve is a curve often used in radiobiology that represents the relationship between the amount of cells retaining reproductive capabilities and the absorbed dose of radiation from said cells.
The OER is reduced for low doses as evaluated for cultured mammalian cells exposed to x-rays under aerobic (21% O2, 159 mmHg) and anoxic (nitrogen) conditions. [17] Typical fractionation treatments are daily 2 Gy exposures, as below this dose the so-called 'shoulder' or repair region of the cell survival curve is encroached upon reducing the ...
The blue line is for cells which were not given a chance to recover; the red line is for cells which were allowed to stand for a time and recover. In the graph to the right, called a cell survival curve, the dose vs. surviving fraction have been drawn for a hypothetical group of cells with and without a rest time for the cells to recover. Other ...
g2: % of cells in G2 phase; grade: tumor grade (1-4) gleason: Gleason grade (3-10) The survival tree produced by the analysis is shown in the figure. Survival tree for prostate cancer data set. Each branch in the tree indicates a split on the value of a variable.
Typically the evaluation of relative biological effectiveness is done on various types of living cells grown in culture medium, including prokaryotic cells such as bacteria, simple eukaryotic cells such as single celled plants, and advanced eukaryotic cells derived from organisms such as rats. By irradiating batches of cells with different ...
In the graph on left, a dose/survival curve for a hypothetical group of cells has been drawn with and without a rest time for the cells to recover. Other than the recovery time partway through the irradiation, the cells would have been treated identically. Radioresistance may be induced by exposure to small doses of ionizing radiation.
A clonogenic assay is a cell biology technique for studying the effectiveness of specific agents on the survival and proliferation of cells. It is frequently used in cancer research laboratories to determine the effect of drugs or radiation on proliferating tumor cells [1] as well as for titration of Cell-killing Particles (CKPs) in virus stocks. [2]
Cell survival curve; D. DaT scan; Deep inspiration breath-hold; Dosimetry; E. Effective dose (radiation) Effects of nuclear explosions on human health;