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Vitamin C administration may also acidify the urine and could promote the precipitation of kidney stones or drugs in the urine. [20] Although vitamin C can be well tolerated at doses well above what government organizations recommend, adverse effects can occur at doses above 3 grams per day.
Vitamin C- Water-soluble vitamin that aids in keeping tissues healthy, wound healing, and infection prevention. [2] Vitamin D- Normally, the kidney changes vitamin D into its active form, vitamin D3, which helps with calcium absorption. Many dialysis patients have low intakes of calcium due to avoidance of foods containing phosphorus and potassium.
Vitamin C has a definitive role in treating scurvy, which is a disease caused by vitamin C deficiency. Beyond that, a role for vitamin C as prevention or treatment for various diseases is disputed, with reviews often reporting conflicting results. No effect of vitamin C supplementation reported for overall mortality. [105]
Men in both studies, on a diet devoid or nearly devoid of vitamin C, had blood levels of vitamin C too low to be accurately measured when they developed signs of scurvy, and in the Iowa study, at this time were estimated (by labeled vitamin C dilution) to have a body pool of less than 300 mg, with daily turnover of only 2.5 mg/day. [91]
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The US Recommended Dietary Allowance for vitamin C for adult women is 76 mg/day and for adult men 90 mg/day. Although Linus Pauling was known for highly respectable research in chemistry and biochemistry, he was also known for promoting the consumption of vitamin C in large doses. [ 25 ]
The evidence linking vitamin C supplements with an increased rate of kidney stones is inconclusive. [38] [39] The excess dietary intake of vitamin C might increase the risk of calcium-oxalate stone formation. [40] The link between vitamin D intake and kidney stones is also tenuous.
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