Search results
Results from the WOW.Com Content Network
Genetic polymorphism is actively and steadily maintained in populations by natural selection, in contrast to transient polymorphisms where a form is progressively replaced by another. [15]: 6–7 By definition, genetic polymorphism relates to a balance or equilibrium between morphs.
Polymorphisms can be identified in the laboratory using a variety of methods. Many methods employ PCR to amplify the sequence of a gene. Once amplified, polymorphisms and mutations in the sequence can be detected by DNA sequencing, either directly or after screening for variation with a method such as single strand conformation polymorphism analysis.
A genetic polymorphism means that different forms of particular genes, and hence of the proteins that they produce, are co-existing within a species. Selectionists claimed that such polymorphisms are maintained by balancing selection, while neutralists view the variation of a protein as a transient phase of molecular evolution. [1]
Segregating sites are positions which show differences (polymorphisms) between related genes in a sequence alignment (are not conserved). [1] Segregating sites include conservative, semi-conservative and non-conservative mutations.
In 1973, M. J. D. White, then at the end of a long career investigating karyotypes, gave an interesting summary of the distribution of chromosome polymorphism. "It is extremely difficult to get an adequate idea as to what fraction of the species of eukaryote organisms actually are polymorphic for structural rearrangements of the chromosomes.
A rare example of sympatric speciation in animals is the divergence of "resident" and "transient" orca forms in the northeast Pacific. [26] Resident and transient orcas inhabit the same waters, but avoid each other and do not interbreed. The two forms hunt different prey species and have different diets, vocal behaviour, and social structures.
Polymorphism can be distinguished by when the implementation is selected: statically (at compile time) or dynamically (at run time, typically via a virtual function). This is known respectively as static dispatch and dynamic dispatch, and the corresponding forms of polymorphism are accordingly called static polymorphism and dynamic polymorphism.
Transient expression, more frequently referred to "transient gene expression", is the temporary expression of genes that are expressed for a short time after nucleic acid, most frequently plasmid DNA encoding an expression cassette, has been introduced into eukaryotic cells with a chemical delivery agent like calcium phosphate (CaPi) or polyethyleneimine (PEI). [1]