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  2. Gene therapy of the human retina - Wikipedia

    en.wikipedia.org/wiki/Gene_therapy_of_the_human...

    Following the successful clinical trials in LCA, researchers have been developing similar treatments using adeno-associated virus for age-related macular degeneration (AMD). To date, efforts have focused on long-term delivery of VEGF inhibitors to treat the wet form of macular degeneration. Whereas wet AMD is currently treated using frequent ...

  3. Macular degeneration - Wikipedia

    en.wikipedia.org/wiki/Macular_degeneration

    The incidence of age-related macular degeneration and its associated features increases with age and is low in people <55 years of age. [101] Smoking is the strongest modifiable risk factor. [102] As of 2008, age-related macular degeneration accounts for more than 54% of all vision loss in the white population in the US. [103]

  4. Retinal implant - Wikipedia

    en.wikipedia.org/wiki/Retinal_implant

    A retinal implant is a visual prosthesis for restoration of sight to patients blinded by retinal degeneration. The system is meant to partially restore useful vision to those who have lost their photoreceptors due to retinal diseases such as retinitis pigmentosa (RP) or age-related macular degeneration (AMD).

  5. Stem cell therapy for macular degeneration - Wikipedia

    en.wikipedia.org/wiki/Stem_cell_therapy_for...

    Induced pluripotent stem cell taken from blood cell and converted in retinal pigment epithelium. Stem cell therapy for macular degeneration is an emerging treatment approach aimed at restoring vision in individuals suffering from various forms of macular degeneration, particularly age-related macular degeneration (AMD). [1]

  6. Retinal regeneration - Wikipedia

    en.wikipedia.org/wiki/Retinal_regeneration

    In February 2013, the US Food and Drug Administration approved the use of the Argus II Retinal Prosthesis System , [11] making it the first FDA-approved implant to treat retinal degeneration. The device may help adults with RP who have lost the ability to perceive shapes and movement to be more mobile and to perform day-to-day activities.

  7. Anti-VEGF - Wikipedia

    en.wikipedia.org/wiki/Anti-VEGF

    A 2014 Cochrane Systematic Review studied the effectiveness of ranibizumab and pegaptanib, on patients who have macular edema caused by central retinal vein occlusion. [5] Participants in both treatment groups showed improvement in visual acuity measures and a reduction in macular edema symptoms over six months. [5]

  8. Geographic atrophy - Wikipedia

    en.wikipedia.org/wiki/Geographic_atrophy

    Fundus of geographic atrophy. Geographic atrophy (GA), also known as atrophic age-related macular degeneration (AMD) or advanced dry AMD, is an advanced form of age-related macular degeneration that can result in the progressive and irreversible loss of retinal tissue (photoreceptors, retinal pigment epithelium, choriocapillaris) which can lead to a loss of central vision over time.

  9. Maculopathy - Wikipedia

    en.wikipedia.org/wiki/Maculopathy

    Age-Related Macular Degeneration is a degenerative maculopathy associated with progressive sight loss. It is characterised by changes in pigmentation in the Retinal Pigment Epithelium, the appearance of drusen on the retina of the eye and choroidal neovascularization. AMD has two forms; 'dry' or atrophic/non-exudative AMD, and 'wet' or ...

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