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The HLA rules describe the responsibilities of federations and the federates that join. [12] Federations shall have an HLA federation object model (FOM), documented in accordance with the HLA object model template (OMT). In a federation, all representation of objects in the FOM shall be in the federates, not in the run-time infrastructure (RTI).
In simulation, run-time infrastructure (RTI) is a middleware that is required when implementing the High Level Architecture (HLA). RTI is the fundamental component of HLA. It provides a set of software services that are necessary to support federates to coordinate their operations and data exchange during a runtime execution. In other sense, it ...
HLA region of Chromosome 6. The human leukocyte antigen (HLA) system is a complex of genes on chromosome 6 in humans that encode cell-surface proteins responsible for regulation of the immune system. [1] The HLA system is also known as the human version of the major histocompatibility complex (MHC) found in many animals. [2]
Human leukocyte antigen (HLA) alleles associated with conditions of or affecting the human integumentary system Condition Associated HLA allele(s) Fixed drug eruption: B22 Lichen planus: DR1 DR2 DRw9 DR10 Bw15 B8 Psoriasis: Cw6 DR406 Psoriatic arthritis: B27 Ankylosing spondylitis: B27 Reactive arthritis: B27 Acute anterior uveitis: B27 Behçet ...
HLA-NET is a network targeted to the study of Human leukocyte antigen (HLA) from a populational point of view. The network was initiated by COST Action BM0803 [ 1 ] in January 2009. Currently HLA-NET activities are being coordinated by a subcommittee of the scientific committee of the European Federation for Immunogenetics .
HLA research didn't heat up until the 1980s when a group of researchers finally elucidated the shape of the HLA-A*02 protein (just one of many specific HLA proteins). [1] Even more recently, in 2010, the WHO committee responsible for naming all HLA proteins revised their standards for naming to introduce more clarity and specificity in the ...
Another version of the HLA-B gene, HLA-B53, has been shown to help protect against severe malaria. [4] HLA-B53 is most common in West African populations, where malaria is a frequent cause of death in children. Researchers suggest that this version of the HLA-B gene may help the immune system respond more effectively to the parasite that causes ...
In academia, computational immunology is a field of science that encompasses high-throughput genomic and bioinformatics approaches to immunology.The field's main aim is to convert immunological data into computational problems, solve these problems using mathematical and computational approaches and then convert these results into immunologically meaningful interpretations.