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Arginine alpha-ketoglutarate (AAKG) is a salt of the amino acid arginine and alpha-ketoglutaric acid. It is marketed as a bodybuilding supplement. [1] Peer-reviewed studies have found no increase in muscle protein synthesis or improvement in muscle strength from use of AAKG as a dietary supplement. [1] [2] [3]
L-arginine is recognized as safe (GRAS-status) at intakes of up to 20 grams per day. [51] L-arginine is found in many foods, such as fish, poultry, and dairy products, and is used as a dietary supplement. [52] It may interact with various prescription drugs and herbal supplements. [52]
Creating an industry estimated to have a value of $151.9 billion in 2021, [4] there are more than 50,000 dietary supplement products marketed in the United States, [5] where about 50% of the American adult population consumes dietary supplements. Multivitamins are the most commonly used product among types of dietary supplements. [6]
l-Arginine ethyl ester is a white powder quickly soluble in hot water. It has a characteristically bad and bitter taste, thus before drinking it is recommended to mix the powder with a strongly flavored beverage or citrus juice. [dubious – discuss] Arginine ethyl ester falls under the category of protected aminoacids.
[1] [2] Chemically, it is a methyl derivative of the amino acid arginine. It is used as a biochemical tool in the study of physiological role of nitric oxide . The inhibiting effect of N -methylarginine on vasodilation is lower in hypertensive patients than in normal subjects, indicating endothelial dysfunction . [ 3 ]
L-Arginine:glycine amidinotransferase (AGAT; EC 2.1.4.1) is the enzyme that catalyses the transfer of an amidino group from L-arginine to glycine. The products are L-ornithine and glycocyamine, also known as guanidinoacetate, the immediate precursor of creatine. Creatine and its phosphorylated form play a central role in the energy metabolism ...
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