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Hallucinogens are a large and diverse class of psychoactive drugs that can produce altered states of consciousness characterized by major alterations in thought, mood, and perception as well as other changes. [1] [2] Most hallucinogens can be categorized as either being psychedelics, dissociatives, or deliriants. [2]
[82] [10] In addition, there is a strong correlation between hallucinogenic potency in humans and potency in the HTR assay. [10] [87] Moreover, the HTR paradigm is one of the only animal tests that can distinguish between hallucinogenic serotonin 5-HT 2A receptor agonists and non-hallucinogenic serotonin 5-HT 2A receptor agonists, such as ...
Although hallucinogenic Psilocybe species are abundant in low-lying areas of Mexico, most ceremonial use takes places in mountainous areas of elevations greater than 1,500 meters (4,900 ft). Guzmán suggests this is a vestige of Spanish colonial influence from several hundred years earlier, when mushroom use was persecuted by the Catholic Church .
Salvia divinorum, a dissociative hallucinogenic sage. This is a list of plant species that, when consumed by humans, are known or suspected to produce psychoactive effects: changes in nervous system function that alter perception, mood, consciousness, cognition or behavior.
In the early 1960s the use of LSD and other hallucinogens was advocated by new proponents of consciousness expansion such as Leary, Huxley, Alan Watts and Arthur Koestler, [182] [183] and according to L. R. Veysey they profoundly influenced the thinking of the new generation of youth. [184]
(The Center Square) – The U.S. Embassy in Peru has warned travelers not use a potent hallucinogenic brew often referred to as ayahuasca or kambo after several deaths in 2024. Ayahuasca use has ...
Between 2013 and 2017, archaeological excavations at the Quilcapampa site in southern Peru, found that the Wari used seeds from the vilca tree and combined the hallucinogenic drug with chicha, or beer made from the molle tree. [117] Psilocybin mushroom + cocoa [dubious – discuss] Theobroma cacao: Bean: Theobromine, small amount of MAOIs Stimulant
But experts also warn that taking psilocybin and other hallucinogens comes with potential health risks, such as psychosis or other longer-term mental health issues in some, as well as physical ...