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  2. Neurogenic claudication - Wikipedia

    en.wikipedia.org/wiki/Neurogenic_claudication

    Less commonly, the cause of spinal stenosis may be present at birth as seen in achondroplasia, spina bifida, and certain mucopolysaccharidoses. [15] In addition to spinal stenosis, other lower back conditions such as spondylosis, tumors, infections and herniated or ruptured discs can cause NC. These conditions contribute to the potential ...

  3. Gabapentin - Wikipedia

    en.wikipedia.org/wiki/Gabapentin

    The oral bioavailability of gabapentin is approximately 80% at 100 mg administered three times daily once every 8 hours, but decreases to 60% at 300 mg, 47% at 400 mg, 34% at 800 mg, 33% at 1,200 mg, and 27% at 1,600 mg, all with the same dosing schedule.

  4. Gabapentinoid - Wikipedia

    en.wikipedia.org/wiki/Gabapentinoid

    The oral bioavailability of gabapentin is approximately 80% at 100 mg administered three times daily once every 8 hours, but decreases to 60% at 300 mg, 47% at 400 mg, 34% at 800 mg, 33% at 1,200 mg, and 27% at 1,600 mg, all with the same dosing schedule.

  5. Spinal stenosis - Wikipedia

    en.wikipedia.org/wiki/Spinal_stenosis

    Such severe spinal stenosis symptoms are virtually absent in lumbar stenosis, however, as the spinal cord terminates at the top end of the adult lumbar spine, with only nerve roots (cauda equina) continuing further down. [15] Cervical spinal stenosis is a condition involving narrowing of the spinal canal at the level of the neck.

  6. Claudication - Wikipedia

    en.wikipedia.org/wiki/Claudication

    Spinal or neurogenic claudication may be differentiated from arterial claudication based on activity and position. In neurogenic claudication, positional changes lead to increased stenosis (narrowing) of the spinal canal and compression of nerve roots and resultant lower extremity symptoms. Standing and extension of the spine narrows the spinal ...

  7. Spinal disease - Wikipedia

    en.wikipedia.org/wiki/Spinal_disease

    Lumbar spinal stenosis is very prevalent with 9.3% of the general population producing symptoms and the number is continuing to rise in patients older than 60. [16] It's generally an indication for spinal surgery in patients older than 65 years of age. [17]

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