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Example representation of the environmental factors characterizing the exposome. The exposome is a concept used to describe environmental exposures that an individual encounters throughout life, and how these exposures impact biology and health. It encompasses both external and internal factors, including chemical, physical, biological, and ...
The Toxin and Toxin-Target Database (T3DB), [1] [2] also known as the Toxic Exposome Database, is a freely accessible online database of common substances that are toxic to humans, along with their protein, DNA or organ targets. The database currently houses nearly 3,700 toxic compounds or poisons described by nearly 42,000 synonyms.
The exposome encompasses the set of human environmental (i.e. non-genetic) exposures from conception onwards, complementing the genome. The exposome was first proposed in 2005 by cancer epidemiologist Christopher Paul Wild in an article entitled "Complementing the genome with an "exposome": the outstanding challenge of environmental exposure ...
Human history or world history is the record of humankind from prehistory to the present. Modern humans evolved in Africa around 300,000 years ago and initially lived as hunter-gatherers . They migrated out of Africa during the Last Ice Age and had spread across Earth's continental land except Antarctica by the end of the Ice Age 12,000 years ago.
These timelines of world history detail recorded events since the creation of writing roughly 5000 years ago to the present day. For events from c. 3200 BC – c. 500 see: Timeline of ancient history; For events from c. 500 – c. 1499, see: Timeline of post-classical history; For events from c. 1500, see: Timelines of modern history
Also pre-literary history. The period of human history between the use of the first stone tools by hominin apes (c. 3.3 million years ago) and the invention of the earliest forms of writing (c. 5,000 years ago), the latter of which marks the beginning of conventional history. The distinction between prehistory and history – i.e. between those ...
Exposome-NL is a 10-year Dutch research program of multiple Dutch universities collaborating in the field of exposome research. Researchers from fields such as exposure science, environmental science, cardiovascular and metabolic health, clinical epidemiology, nutritional epidemiology, geosciences, agent-based modelling, molecular biology, chemistry and bioinformatics, and biostatistics ...
The question of what constitutes history, and whether there is an effective method for interpreting recorded history, is raised in the philosophy of history as a question of epistemology. The study of different historical methods is known as historiography , which focuses on examining how different interpreters of recorded history create ...