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Alendronic acid, sold under the brand name Fosamax among others, is a bisphosphonate medication used to treat osteoporosis and Paget's disease of bone. [4] It is taken by mouth. [ 4 ] Use is often recommended together with vitamin D , calcium supplementation , and lifestyle changes.
In June 2010, denosumab was approved by the FDA for use in postmenopausal women with risk of osteoporosis [37] under the brand name Prolia, [38] and in November 2010, as Xgeva for the prevention of skeleton-related events in people with bone metastases from solid tumors. [39] Denosumab is the first RANKL inhibitor to be approved by the FDA. [37]
In large studies, women taking bisphosphonates for osteoporosis have had unusual fractures ("bisphosphonate fractures") in the femur (thigh bone) in the shaft (diaphysis or sub-trochanteric region) of the bone, rather than at the femoral neck, which is the most common site of fracture. However, these fractures are rare (12 in 14,195 women ...
Prolia, approved in 2010 to treat bone loss in postmenopausal women and later approved to treat men and women at high risk of fracture, brought in total third-quarter sales of $986 million.
With oral osteoporosis, the emphasis should be on good nutrient absorption and metabolic wastes elimination through a healthy gastro-intestinal function, effective hepatic metabolism of toxicants such as exogenous estrogens, endogenous acetaldehyde and heavy metals, a balanced diet, healthy lifestyle, assessment of factors related to potential ...
The APA recommends cultivating a support system of colleagues, family, and friends to reduce stress through socializing and prioritizing self-care, which can be as simple as sleeping soundly ...
They are used for the treatment of osteoporosis and other bone disorders that cause bone fragility and diseases where bone resorption is excessive. Osteoporosis is common in post-menopausal women and patients in corticosteroid treatment where biphosphonates have been proven a valuable treatment and also used successfully against Paget's disease ...
You've likely seen warnings against taking aspirin as a preventative measure against heart attack and stroke. It isn't quite that simple.