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  2. Chemical polarity - Wikipedia

    en.wikipedia.org/wiki/Chemical_polarity

    Polar molecules must contain one or more polar bonds due to a difference in electronegativity between the bonded atoms. Molecules containing polar bonds have no molecular polarity if the bond dipoles cancel each other out by symmetry. Polar molecules interact through dipole-dipole intermolecular forces and hydrogen bonds.

  3. Hydrophobicity scales - Wikipedia

    en.wikipedia.org/wiki/Hydrophobicity_scales

    Polar chemical groups, such as OH group in methanol do not cause the hydrophobic effect. However, a pure hydrocarbon molecule, for example hexane , cannot accept or donate hydrogen bonds to water. Introduction of hexane into water causes disruption of the hydrogen bonding network between water molecules.

  4. Solvent - Wikipedia

    en.wikipedia.org/wiki/Solvent

    The polarity, dipole moment, polarizability and hydrogen bonding of a solvent determines what type of compounds it is able to dissolve and with what other solvents or liquid compounds it is miscible. Generally, polar solvents dissolve polar compounds best and non-polar solvents dissolve non-polar compounds best; hence "like dissolves like".

  5. Hydroxy group - Wikipedia

    en.wikipedia.org/wiki/Hydroxy_group

    The hydroxy group is pervasive in chemistry and biochemistry. Many inorganic compounds contain hydroxyl groups, including sulfuric acid, the chemical compound produced on the largest scale industrially. [2] Hydroxy groups participate in the dehydration reactions that link simple biological molecules into long chains.

  6. Alcohol (chemistry) - Wikipedia

    en.wikipedia.org/wiki/Alcohol_(chemistry)

    The red and white balls represent the hydroxyl group (−OH). The three "R"s stand for carbon substituents or hydrogen atoms. [1] In chemistry, an alcohol (from Arabic al-kuḥl 'the kohl'), [2] is a type of organic compound that carries at least one hydroxyl (−OH) functional group bound to a saturated carbon atom.

  7. Hydrophobic effect - Wikipedia

    en.wikipedia.org/wiki/Hydrophobic_effect

    [1] [2] The word hydrophobic literally means "water-fearing", and it describes the segregation of water and nonpolar substances, which maximizes the entropy of water and minimizes the area of contact between water and nonpolar molecules. In terms of thermodynamics, the hydrophobic effect is the free energy change of water surrounding a solute. [3]

  8. Aqueous normal-phase chromatography - Wikipedia

    en.wikipedia.org/wiki/Aqueous_normal-phase...

    In reversed phase chromatography, the most polar compounds elute first with the more nonpolar compounds eluting later. The mobile phase is generally a mixture of water and miscible polarity-modifying organic solvent, such as methanol, acetonitrile or THF. Retention increases as the fraction of the polar solvent (water) in the mobile phase is ...

  9. Hydroxymethyl group - Wikipedia

    en.wikipedia.org/wiki/Hydroxymethyl_group

    It consists of a methylene bridge (−CH 2 − unit) bonded to a hydroxyl group (−OH). This makes the hydroxymethyl group an alcohol . It has the identical chemical formula with the methoxy group ( −O−CH 3 ) that differs only in the attachment site and orientation to the rest of the molecule.

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