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The TMC joint is a synovial joint between the trapezium bone of the wrist and the metacarpal bone at the base of the thumb. This joint is a so-called saddle joint (articulatio sellaris), unlike the CMC joints of the other four fingers which are ellipsoid joints. [17] This means that the surfaces of the TMC joint are both concave and convex.
Hypertrophic osteoarthropathy is one of many distant effect disorders due to cancer, with lung cancer being the most common cause but also occurring with ovarian or adrenal malignancies. A distant effect disorder, or a paraneoplastic syndrome , affects distant areas and thus is not related to local compression or obstruction effects from the tumor.
The most common initial presenting symptom of wrist osteoarthritis is joint pain. [7] [8] Other signs and symptoms, as with any joint affected by osteoarthritis, include: Loss of motion stiffness, which can be worse after a period of rest, such as when one awakes in the morning. Deformity of the wrist.
Joint pain is a common symptom we all experience at some point or another. Painful joints can have a significant impact on quality of life and the ability to do daily activities.
Other rheumatological disorders that can cause the features typical for RS3PE include late onset (seronegative) rheumatoid arthritis, acute sarcoidosis, ankylosing spondylitis and other spondyloarthropathies such as psoriatic arthropathy, mixed connective tissue disease, chondrocalcinosis and arthropathy due to amyloidosis. [6] [9]
The disease generally affects only one of the larger weight bearing joints (hip, ankle, knee) – although the elbow, and wrist can also be affected. It rarely involves the temporomandibular joint (TMJ) and most publications are case reports. [3] Synovial chondromatosis occurs twice as commonly in males as females and usually in their forties.
Men without prostate cancer typically have PSA levels of under 4 nanograms per milliliter (ng/mL), according to the American Cancer Society. PSA levels between 4 and 10 suggest you could have ...
Prostate cancer is one of the most common types of cancer in men, ranking only behind lung cancer in deaths. About 1 in 8 men will be diagnosed with prostate cancer during their lives, according ...