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On gross pathology, nephrosclerosis manifests as a fine granular surface. [4]"Hypertensive" refers to high blood pressure and "nephropathy" means damage to the kidney; hence this condition is where chronic high blood pressure causes damages to kidney tissue; this includes the small blood vessels, glomeruli, kidney tubules and interstitial tissues.
Secondary causes of nephrotic syndrome have the same histologic patterns as the primary causes, though they may exhibit some differences suggesting a secondary cause, such as inclusion bodies. [24] They are usually described by the underlying cause, such as: [citation needed] Diabetic nephropathy: is a complication that occurs in some diabetics ...
Pneumonoultramicroscopicsilicovolcanoconiosis is the longest word in the English language.The word can be analysed as follows: Pneumono: from ancient Greek (πνεύμων, pneúmōn) which means lungs
Lung cancer is the most diagnosed and deadliest cancer worldwide, with 2.2 million cases in 2020 resulting in 1.8 million deaths. [3] Lung cancer is rare in those younger than 40; the average age at diagnosis is 70 years, and the average age at death 72. [2] Incidence and outcomes vary widely across the world, depending on patterns of tobacco use.
Focal segmental glomerulosclerosis is a disease that attacks the kidney's filtering system causing serious scarring and thus a cause of nephrotic syndrome in children and adolescents, [1] as well as an important cause of kidney failure in adults. Hippocampal sclerosis, a brain damage often seen in individuals with temporal lobe epilepsy.
Lung cancer is the overall leading cause of cancer deaths across the nation. The American Cancer Society estimates that about 226,000 new cases of lung cancer will be diagnosed in 2025, and nearly ...
Many causes of secondary FSGS contribute to podocyte injury through hyperfiltration, which is a scenario of excess filtration by renal glomeruli. [24] Hyperfiltration can be caused by obesity, diabetes or loss of the contralateral kidney, among other causes. [24] Secondary FSGS can also be caused by toxins, including anabolic steroids and heroin.
Benign nephrosclerosis alone hardly ever causes severe damage to the kidney, except in susceptible populations, such as African Americans, where it may lead to uremia and death. However, all persons with this disease usually show some functional impairment, such as loss of concentration or a variably diminished GFR.