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  2. Fenfluramine/phentermine - Wikipedia

    en.wikipedia.org/wiki/Fenfluramine/phentermine

    Upon the release of the information regarding fen-phen's cardiac risks, the Association of Trial Lawyers of America formed a large trial lawyer group to seek damages from American Home Products, the distributor of fenfluramine and dexfenfluramine. [14] Fen-phen is no longer widely available. In April 2005, American Lawyer magazine ran a cover ...

  3. Fenfluramine - Wikipedia

    en.wikipedia.org/wiki/Fenfluramine

    Fenfluramine was an appetite suppressant which was used to treat obesity. [8] It was used both on its own and, in combination with phentermine, as part of the anti-obesity medication Fen-Phen. [8] In June 2020, fenfluramine was approved for medical use in the United States with an indication to treat Dravet syndrome. [7] [38]

  4. Phentermine - Wikipedia

    en.wikipedia.org/wiki/Phentermine

    [9] [10] Phentermine was withdrawn from the market in the United Kingdom in 2000, while the combination medication fen-phen, of which it was a part, was withdrawn from the market in 1997 due to side effects [11] of fenfluramine which caused increased levels of circulating serotonin which stimulated serotonin receptors on heart valves and thus ...

  5. From the Greeks to GLP-1s: The Complete History of Weight ...

    www.aol.com/greeks-glp-1s-complete-history...

    The FDA approved a new central nervous system stimulant called phentermine for weight loss in 1959. ... A short-lived weight loss medication emerged in the 1990s with the introduction of fen-phen ...

  6. Dexfenfluramine - Wikipedia

    en.wikipedia.org/wiki/Dexfenfluramine

    It is the d-enantiomer of fenfluramine and is structurally similar to amphetamine, but lacks any psychologically stimulating effects. Dexfenfluramine was, for some years in the mid-1990s, approved by the United States Food and Drug Administration for the purposes of weight loss .

  7. Lucien Abenhaim - Wikipedia

    en.wikipedia.org/wiki/Lucien_Abenhaim

    Fenfluramine was the main toxic component of the so-called ‘fen-phen’ combination. He led the renowned International Primary Pulmonary Hypertension Study (IPPHS), which was published in the prestigious New England Journal of Medicine in 1996, and which showed that fenfluramine had a causal role in primary pulmonary hypertension, a fatal ...

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    Get AOL Mail for FREE! Manage your email like never before with travel, photo & document views. Personalize your inbox with themes & tabs. You've Got Mail!

  9. Anorectic - Wikipedia

    en.wikipedia.org/wiki/Anorectic

    Epidemics of fatal pulmonary hypertension and heart valve damage associated with pharmaceutical anorectic agents have led to the withdrawal of products from the market. This was the case with aminorex in the 1960s, and again in the 1990s with fenfluramine (see: Fen-phen). [7]

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