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  2. Mast Cell Activation Syndrome - Cleveland Clinic

    my.clevelandclinic.org/health/diseases/mast-cell-activation-syndrome

    Mast cell activation syndrome (MCAS) is when your mast cells overreact with no known trigger. It causes severe symptoms and can lead to life-threatening anaphylaxis.

  3. Systemic mastocytosis - Symptoms and causes - Mayo Clinic

    www.mayoclinic.org/diseases-conditions/systemic-mastocytosis/symptoms-causes/...

    Systemic mastocytosis (mas-to-sy-TOE-sis) is a rare disorder that results in too many mast cells building up in your body. A mast cell is a type of white blood cell. Mast cells are found in connective tissues throughout your body.

  4. Mast Cell Activation Syndrome: Symptoms, Causes, and Treatment - ...

    www.webmd.com/allergies/what-is-mast-cell-activation-syndrome

    Mast cell activation syndrome, also called MCAS or mast cell activation disorder, is a condition that causes mast cells to release high amounts of chemicals into your body.

  5. Mast cell disorders: An overview - UpToDate

    www.uptodate.com/contents/mast-cell-disorders-an-overview

    Mast cell disorders are conditions in which mast cells are either increased in number, hyper-reactive, or both. These conditions range in severity from relatively benign disorders that do not impact lifespan to malignant clonal diseases that progress rapidly.

  6. Mast Cell Activation Syndrome (MCAS) - American Academy of...

    www.aaaai.org/conditions-treatments/related-conditions/mcas

    MCAS is a condition in which the patient experiences repeated episodes of the symptoms of anaphylaxis – allergic symptoms such as hives, swelling, low blood pressure, difficulty breathing and severe diarrhea. High levels of mast cell mediators are released during those episodes.

  7. Mastocytosis: Types, Symptoms & Treatment - Cleveland Clinic

    my.clevelandclinic.org/health/diseases/5908

    Mastocytosis happens when mast cells that protect your body from allergens and bacteria mutate (change) and become abnormal cells that set up a continuous allergic response. Mastocytosis symptoms can be mild or severe.

  8. What Are Mast Cell Diseases? - Allergy & Asthma Network

    allergyasthmanetwork.org/mast-cell-diseases

    Mast cell diseases are caused by abnormal and/or overly active mast cells. Some people are born with a mast cell disease. Others may get it in childhood or adulthood. Mast cell diseases are rare, but they are increasingly recognized and diagnosed by doctors.

  9. Systemic Mastocytosis: Symptoms & Treatment - Cleveland Clinic

    my.clevelandclinic.org/health/diseases/24386-systemic-mastocytosis

    Systemic mastocytosis is a rare blood disorder. It happens when your body makes abnormal mast cells. Mast cells are white blood cells and part of your immune system. They’re first responders when allergens and other intruders attack your body.

  10. Mast Cell Activation Syndrome (MCAS) - Healthline

    www.healthline.com/health/mast-cell-activation-syndrome

    Mast cell activation syndrome (MCAS) is a condition that occurs when the mast cells in your body release too much of a substance that causes allergy-like symptoms. What is mast cell...

  11. Mast cell diseases are caused by the proliferation and accumulation of genetically altered mast cells and/or the inappropriate release of mast cell mediators, creating symptoms in multiple organ systems. 2 The three major forms of mast cell diseases are mastocytosis, mast cell activation syndrome (MCAS), and Hereditary Alpha tryptasemia (HAT).