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Total body irradiation (TBI) is a form of radiotherapy used primarily as part of the preparative regimen for haematopoietic stem cell (or bone marrow) transplantation. As the name implies, TBI involves irradiation of the entire body, though in modern practice the lungs are often partially shielded to lower the risk of radiation-induced lung ...
Total body irradiation (TBI) is a radiation therapy technique used to prepare the body to receive a bone marrow transplant. Brachytherapy , in which a radioactive source is placed inside or next to the area requiring treatment, is another form of radiation therapy that minimizes exposure to healthy tissue during procedures to treat cancers of ...
The Cincinnati Radiation Experiments were a series of total and partial body irradiation tests performed on at least 90 patients with advanced cancer at the Cincinnati General Hospital, now University of Cincinnati Hospital, from 1960 to 1971. Led by radiologist Eugene L. Saenger, the experiments were funded in part by the Defense Atomic ...
Acute radiation syndrome (ARS), also known as radiation sickness or radiation poisoning, is a collection of health effects that are caused by being exposed to high amounts of ionizing radiation in a short period of time. [ 1 ] Symptoms can start within an hour of exposure, and can last for several months. [ 1 ][ 3 ][ 5 ] Early symptoms are ...
Radiation therapy (or radiotherapy) is used on painful bony areas, in high disease burdens, or as part of the preparations for a bone marrow transplant (total body irradiation). In the past, physicians commonly utilized radiation in the form of whole-brain radiation for central nervous system prophylaxis, to prevent the occurrence and/or ...
Effective dose is a dose quantity in the International Commission on Radiological Protection (ICRP) system of radiological protection. [1]It is the tissue-weighted sum of the equivalent doses in all specified tissues and organs of the human body and represents the stochastic health risk to the whole body, which is the probability of cancer induction and genetic effects, of low levels of ...
The Advisory Committee on Human Radiation Experiments was established in 1994 to investigate questions of the record of the United States government with respect to human radiation experiments. The special committee was created by President Bill Clinton in Executive Order 12891, issued January 15, 1994. Ruth Faden of The Johns Hopkins Berman ...
[33] [39] [40] [41] Lymphodepletion may be achieved by myeloablative chemotherapy, to which total body irradiation may be added for greater effect. [42] Transferred cells multiplied in vivo and persisted in peripheral blood in many people, sometimes representing levels of 75% of all CD8 + T cells at 6–12 months after infusion. [43]