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The Variant Call Format or VCF is a standard text file format used in bioinformatics for storing gene sequence or DNA sequence variations. The format was developed in 2010 for the 1000 Genomes Project and has since been used by other large-scale genotyping and DNA sequencing projects.
If the input file is of the ANNOVAR input format type, then the output will be a TSV by default, with the option to output to CSV if the -csvout parameter is specified. By choosing CSV or TSV as the output file type, a user could open the files to view the annotations in Excel or a different spreadsheet software application. This is a popular ...
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The calculation of prior probabilities depends on available data from the genome being studied, and the type of analysis being performed. For studies where good reference data containing frequencies of known mutations is available (for example, in studying human genome data), these known frequencies of genotypes in the population can be used to estimate priors.
Author: pwei: Short title: Library of Congress Classification Outline; Date and time of digitizing: 16:07, 12 March 2003: File change date and time: 13:31, 22 November 2010
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Genetic variation can be identified at many levels. Identifying genetic variation is possible from observations of phenotypic variation in either quantitative traits (traits that vary continuously and are coded for by many genes, e.g., leg length in dogs) or discrete traits (traits that fall into discrete categories and are coded for by one or a few genes, e.g., white, pink, or red petal color ...
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