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Hydrogels can be used as drug delivery vehicles, for transdermal application, ophthalmic drug delivery, [11] cancer treatment [12] or for wound dressing. [ 7 ] [ 13 ] As a type of water based formulation, hydrogels are generally less greasy and are easier to be removed than oil-based formulations like organogels. [ 6 ]
Colloidal System: Finely divided particles of any substance with diameter lying within 1-100 nm range dispersed in any medium constitute what is termed a "colloidal system solution". It is a two phase system.
The term colloidal suspension refers unambiguously to the overall mixture (although a narrower sense of the word suspension is distinguished from colloids by larger particle size). A colloid has a dispersed phase (the suspended particles) and a continuous phase (the medium of suspension).
Examples are suspensions of rod-like viruses such as the tobacco mosaic virus as well as synthetic macromolecules, such as Li 2 Mo 6 Se 6 nanowire [9] or colloidal suspensions of non-spherical colloidal particles. [10] Cellulose and cellulose derivatives form lyotropic liquid crystal phases as do nanocrystalline (nanocellulose) suspensions. [11]
Parenteral drug delivery: Emulsions serve as carriers for intravenous or intramuscular administration of drugs, solubilizing lipophilic ones while protecting from degradation and decreasing injection site irritation. Examples include propofol as a widely used anesthetic and lipid-based solutions used for total parenteral nutrition delivery.
Milk is an emulsified colloid of liquid butterfat globules of 0.1 to 10 micrometer dispersed within a water-based solution.. Interface and colloid science is an interdisciplinary intersection of branches of chemistry, physics, nanoscience and other fields dealing with colloids, heterogeneous systems consisting of a mechanical mixture of particles between 1 nm and 1000 nm dispersed in a ...
Surface area plays a very important role in drug delivery and per mg of gold, as diameters decrease, the surface areas needed to transport drugs increase to the point where a single 1mL volume of 1.8 nm spherical gold nanoparticles have the same surface area as a cell phone.
Typically, gels are synthesized via sol-gel processing, a wet-chemical technique involving a colloidal solution (sol) that acts as the precursor for an integrated network (gel). There are two possible mechanisms whereby organogels form depending on the physical intermolecular inter-actions, namely the fluid-filled fiber and the solid fiber ...