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Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the large intestine). [5] Signs and symptoms may include blood in the stool , a change in bowel movements , weight loss, abdominal pain and fatigue. [ 9 ]
One study involving more than 1 million people with colon cancer from 2004 to 2015 found that 51.6% of those under 50 were diagnosed with stage three or four cancer, while 40% of people over 50 ...
Colorectal adenocarcinoma is distinguished from a colorectal adenoma (mainly tubular and ⁄or villous adenomas) mainly by invasion through the muscularis mucosae. [ 10 ] In carcinoma in situ (Tis), cancer cells invade into the lamina propria, and may involve but not penetrating the muscularis mucosae.
The incidence of the mutation is between 1 in 10,000 and 1 in 15,000 births. By age 35 years, 95% of individuals with FAP (>100 adenomas) have polyps. Without colectomy, colon cancer is virtually inevitable. The mean age of colon cancer in untreated individuals is 39 years (range 34–43 years). [13]
What are the first signs of colon cancer? As more young people get the disease, a woman shares the symptoms that led to her colon cancer diagnosis at 24.
The descending colon extends from the left colic flexure [2]: 1194 at the upper left part of the abdomen inferior-ward through the left hypochondrium and lumbar regions, along the outer border of the left kidney, [citation needed] ending at the level of the iliac crest [2]: 1194 at the lower left part of the abdomen, [citation needed] being ...
The colorectal adenoma is a benign glandular tumor of the colon and the rectum. It is a precursor lesion of the colorectal adenocarcinoma ( colon cancer ). [ 1 ] [ 2 ] [ 3 ] They often manifest as colorectal polyps .
In most cases the positive result is just due to hemorrhoids; however, it can also be due to diverticulosis, inflammatory bowel disease (Crohn's disease, ulcerative colitis), colon cancer, or polyps. Colonic polypectomy has become a routine part of colonoscopy, allowing quick and simple removal of polyps during the procedure, without invasive ...
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