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The 5′ untranslated region (also known as 5′ UTR, leader sequence, transcript leader, or leader RNA) is the region of a messenger RNA (mRNA) that is directly upstream from the initiation codon. This region is important for the regulation of translation of a transcript by differing mechanisms in viruses , prokaryotes and eukaryotes .
In molecular genetics, the three prime untranslated region (3′-UTR) is the section of messenger RNA (mRNA) that immediately follows the translation termination codon. The 3′-UTR often contains regulatory regions that post-transcriptionally influence gene expression .
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A cluster prime is a prime p such that every even natural number k ≤ p − 3 is the difference of two primes not exceeding p. 3 , 5 , 7 , 11 , 13 , 17 , 19 , 23 , ... ( OEIS : A038134 )
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For example, 3 is a Mersenne prime as it is a prime number and is expressible as 2 2 − 1. [1] [2] The exponents p corresponding to Mersenne primes must themselves be prime, although the vast majority of primes p do not lead to Mersenne primes—for example, 2 11 − 1 = 2047 = 23 × 89. [3]
In molecular biology, the five-prime cap (5′ cap) is a specially altered nucleotide on the 5′ end of some primary transcripts such as precursor messenger RNA. This process, known as mRNA capping , is highly regulated and vital in the creation of stable and mature messenger RNA able to undergo translation during protein synthesis .
Protégé is a free, open source ontology editor and a knowledge management system. The Protégé meta-tool was first built by Mark Musen in 1987 and has since been developed by a team at Stanford University. [4]