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  2. Saliva testing - Wikipedia

    en.wikipedia.org/wiki/Saliva_testing

    Saliva nitric test strip (Berkeley Test) showing colored scale of nitric oxide status – See article and jump to Cardiovascular Disease, Nitric Oxide: a salivary biomarker for cardio-protection Saliva testing or Salivaomics is a diagnostic technique that involves laboratory analysis of saliva to identify markers of endocrine , immunologic ...

  3. Cortisol - Wikipedia

    en.wikipedia.org/wiki/Cortisol

    Test results should, therefore, always be interpreted using the reference range from the laboratory that produced the result. [ 57 ] [ 58 ] [ 59 ] An individual's cortisol levels can be detected in blood, serum, urine, saliva, and sweat.

  4. Adrenal insufficiency - Wikipedia

    en.wikipedia.org/wiki/Adrenal_insufficiency

    [2] [3] Dexamethasone should be used as the corticosteroid of choice in these cases as it is the only corticosteroid that will not affect diagnostic test results. [2] [29] To confirm inappropriately low cortisol secretion, testing can include baseline morning cortisol level in the blood or morning cortisol level in the saliva. [2]

  5. Dexamethasone suppression test - Wikipedia

    en.wikipedia.org/wiki/Dexamethasone_suppression_test

    Low-dose and high-dose variations of the test exist. [4] The test is given at low (usually 1–2 mg) and high (8 mg) doses of dexamethasone, and the levels of cortisol are measured to obtain the results. [5] A low dose of dexamethasone suppresses cortisol in individuals with no pathology in endogenous cortisol production.

  6. Cushing's syndrome - Wikipedia

    en.wikipedia.org/wiki/Cushing's_syndrome

    Cushing's syndrome is a collection of signs and symptoms due to prolonged exposure to glucocorticoids such as cortisol. [4] [9] [10] Signs and symptoms may include high blood pressure, abdominal obesity but with thin arms and legs, reddish stretch marks, a round red face due to facial plethora, [11] a fat lump between the shoulders, weak muscles, weak bones, acne, and fragile skin that heals ...

  7. 11-Deoxycortisol - Wikipedia

    en.wikipedia.org/wiki/11-Deoxycortisol

    11-Deoxycortisol in mammals has limited glucocorticoid activity, but it is the direct precursor of the major mammalian glucocorticoid, cortisol. [15] As a result, the level of 11-deoxycortisol is measured to diagnose impaired cortisol synthesis, to find out the enzyme deficiency that causes impairment along the pathway to cortisol, and to differentiate adrenal disorders.

  8. Pseudo-Cushing's syndrome - Wikipedia

    en.wikipedia.org/wiki/Pseudo-Cushing's_syndrome

    In the alcoholic patient with pseudo-Cushing's, admission to hospital (and avoidance of alcohol) will result in normal midnight cortisol levels within five days, excluding Cushing's [6] Another cause for Cushing's syndrome is adrenocortical carcinoma. This is a rare form of cancer with an incidence of 1-2 per million people annually.

  9. 11β-Hydroxysteroid dehydrogenase - Wikipedia

    en.wikipedia.org/wiki/11β-Hydroxysteroid...

    Cortisol, a glucocorticoid, binds the glucocorticoid receptor. However, because of its molecular similarity to aldosterone it also binds the mineralcorticoid receptor at higher concentrations. Both aldosterone and cortisol have a similar affinity for the mineralocorticoid receptor; however, there is vastly more cortisol in circulation than ...

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