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Colchicine is a medication used to prevent and treat gout, [3] [4] to treat familial Mediterranean fever [5] and Behçet's disease, [6] and to reduce the risk of myocardial infarction. [7] The American College of Rheumatology recommends colchicine, nonsteroidal anti-inflammatory drugs (NSAIDs) or steroids in the treatment of gout.
OTC Bayer medication with child-resistant packaging (cap) and tamper-resistant carton and innerseal Photo of the packaging of four medicines dispensed in the United Kingdom showing their Product Licence Numbers and symbols denoting if they are Prescription Only Medicine (POM) or Pharmacy Medicine (P), or lacking either, denoting General Sales List (GSL).
Probenecid with colchicine is a combination medication used to treat gout. Brand names include ColBenemid, Col-Probenecid, and Proben-C. [1] References
Plants in this genus contain toxic amounts of the alkaloid colchicine which is used pharmaceutically to treat gout and Familial Mediterranean fever. [13] The use of the roots and seeds in traditional medicine is thought to have arisen due to the presence of this drug. [14] Its leaves, corm and seeds are poisonous.
Colchicine is an anti-inflammatory drug that has been in continuous use for more than 3000 years. Colchicine is an oral drug, known to be used for treating acute gout and preventing acute attacks of familial Mediterranean fever (FMF). However, the use of colchicine is limited by its high toxicity in other therapies.
[full citation needed] Colchicine was used as a chemical agent to double the chromosomes. [12] After these developments, a new era of triticale breeding was introduced. Earlier triticale hybrids had four reproductive disorders, namely meiotic instability, high aneuploid frequency, low fertility and shriveled seed (Muntzing 1939; Krolow 1966).
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Colchicine is known to cause alopecia. One case report described a patient who accidentally ate the tubers and then experienced hair loss over her entire body, including complete baldness . [ 12 ] Poisonings can occur when the tubers are mistaken for sweet potatoes [ 11 ] or yams and eaten. [ 12 ]