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Ocrelizumab, sold under the brand name Ocrevus, is a medication used for the treatment of multiple sclerosis.It is a humanized anti-CD20 monoclonal antibody. [8] It targets CD20 marker on B lymphocytes and is an immunosuppressive drug. [10]
In March 2017, ocrelizumab was approved in the United States for the treatment of primary progressive multiple sclerosis in adults. [22] [42] It is also used for the treatment of relapsing forms of multiple sclerosis, to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease in adults. [42]
A three-year controlled study of 60 patients is now being launched at 10 centres across the UK. [119] In another clinical trial, glatiramer acetate (Copaxone) has been combined with mitoxantrone in such a way that every course of mitoxantrone is followed by GA treatment. It has yielded promising results twice, in a consistent way. [120] [121]
Multiple sclerosis (MS) is an autoimmune disorder in which the immune system attacks and destroys the myelin sheath of nerve cells. It most commonly strikes people between the ages of 20 and 40.
She revealed her diagnosis on X, formerly Twitter, later that year. “My symptoms had started in the early part of 2021, and it was literally just tingling on my toes,” Applegate told Roberts.
The second trial was a two-year, multi-center, randomized, double-blind, placebo controlled trial and involved 251 patients. [14] The third trial was a double-blind MRI study involving participation of 239 patients. [15] A 15-year followup of the original trial compared patients who continued with glatiramer to patients who dropped out of the ...
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