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Silver sulfadiazine, sold under the brand Silvadene among others, is a topical antibiotic used in partial thickness and full thickness burns to prevent infection. [1] Tentative evidence has found other antibiotics to be more effective, and therefore it is no longer generally recommended for second-degree (partial-thickness) burns, but is still ...
Silver sulfadiazine (SSD) is a topical antibiotic used in partial thickness and full thickness burns to prevent infection. [4] [21] It was discovered in the 1960s, [22] and was the standard topical antimicrobial for burn wounds for decades.
Kucan JO, Robson MC, Heggers JP, et al. Comparison of silver sulfadiazine, povidone iodine and physiologic saline in the treatment of chronic pressure ulcers. J Am Geriatr Soc 1981;XXIX(5):232-5. In a randomized trial with venous ulcers, SSD one-percent cream was proved to statistically reduce the ulcer size compared to the placebo.
D06BA01 Silver sulfadiazine D06BA02 Sulfathiazole D06BA03 Mafenide D06BA04 Sulfamethizole D06BA05 Sulfanilamide D06BA06 Sulfamerazine QD06BA30 Combinations of chemotherapeutics for topical use D06BA51 Silver sulfadiazine, combinations QD06BA53 Mafenide, combinations QD06BA90 Formosulfathiazole QD06BA99 Sulfonamides, combinations
Sulfadiazine is an antibiotic. [1] Used together with pyrimethamine , a dihydrofolate reductase inhibitor, it is the treatment of choice for toxoplasmosis, which is caused by a protozoan parasite . [ 3 ]
For use as adjunctive therapy for second- and third-degree burns to prevent infection, adults and children should apply topically to a thickness of approximately 1.6 mm to cleaned and debrided wound once or twice per day with a sterile gloved hand. The burned area should be covered with cream at all times. [citation needed]
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