Search results
Results from the WOW.Com Content Network
Extracts from Camptotheca (the "happy tree" or "cancer tree") were used to develop the chemotherapeutic drug Topotecan. Plant sources of anti-cancer agents are plants, the derivatives of which have been shown to be usable for the treatment or prevention of cancer in humans. [1] [2]
Camptothecin (CPT) is a topoisomerase inhibitor.It was discovered in 1966 by M. E. Wall and M. C. Wani in systematic screening of natural products for anticancer drugs.It was isolated from the bark and stem of Camptotheca acuminata (Camptotheca, Happy tree), a tree native to China used in traditional Chinese medicine.
The Madagascan periwinkle Catharanthus roseus L. is the source for a number of important natural products, [1] including catharanthine and vindoline [2] and the vinca alkaloids it produces from them: leurosine and the chemotherapy agents vinblastine [3] and vincristine, [4] all of which can be obtained from the plant.
Anti-Cancer Agents in Medicinal Chemistry is a peer-reviewed academic journal covering the disciplines of medicinal chemistry and drug design relating to chemotherapeutic agents in cancer. It is published by Bentham Science Publishers and the editor-in-chief is Simone Carradori ("G. d'Annunzio" University of Chieti-Pescara). The journal covers ...
Azadiradione acts as an antioxidant and has been used in traditional medicine in Asia, Africa and the Middle East for ages. [1]Research suggests azadiradione may have properties that fight microbes (bacteria, fungi, viruses), [2] reduce inflammation, protect cells from damage, [3] and even have anti-cancer effects.
Because cancer cells spend more time dividing than other cells, inhibiting cell division harms tumor cells more than other cells. Antimetabolite drugs are commonly used to treat leukemia, cancers of the breast, ovary, and the gastrointestinal tract, as well as other types of cancers. [ 4 ]
Aporphine alkaloids present in Litsea glutinosa, a tropical plant with antioxidant and anti-parasitic properties, are claimed to contribute to anti-cancer activity. Research has illustrated the antiproliferative and cytotoxic effects of aporphine-containing extracts of Litsea glutinosa.
With 79% of the Earth's surface covered by water, research into the chemistry of marine organisms is relatively unexplored and represents a vast resource for new medicines to combat major diseases such as cancer, AIDS or malaria. Research typically focuses on sessile organisms or slow moving animals because of their inherent need for chemical ...