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In the 1960s and 1970s, John Vane and others discovered the basic mechanism of aspirin's effects, [3]: 226–231 while clinical trials and other studies from the 1960s to the 1980s established aspirin's efficacy as an anti-clotting agent that reduces the risk of clotting diseases.
Aspirin is also used long-term to help prevent further heart attacks, ischaemic strokes, and blood clots in people at high risk. [10] For pain or fever, effects typically begin within 30 minutes. [10] Aspirin works similarly to other NSAIDs but also suppresses the normal functioning of platelets. [10] One common adverse effect is an upset ...
Seeds likely used for herbalism have been found in archaeological sites of Bronze Age China dating from the Shang dynasty [10] (c. 1600 BCE–c. 1046 BCE). Over a hundred of the 224 drugs mentioned in the Huangdi Neijing – an early Chinese medical text – are herbs. [ 11 ]
Heinrich Dreser, 1897. Heinrich Dreser (1 October 1860 – 21 December 1924) was a German chemist responsible for the aspirin and heroin projects at Bayer AG.He was also a key figure in creating the widely used modern drug codeine.
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In 1899, Bayer launched the compound acetylsalicylic acid under the trademarked name Aspirin. Aspirin is on the World Health Organization's List of Essential Medicines. [5] In 2021, it was the 34th most commonly prescribed medication in the United States, with more than 17 million prescriptions. [6] [7]
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City 1920 369 Altha: Calhoun: 496 1.3 sq mi 3.5 km 2: Mayor–council Town 1946 329 Anna Maria: Manatee: 968 0.74 sq mi 1.9 km 2: Mayor–commission City 1923 278 Apalachicola† Franklin: 2,341 1.9 sq mi 5.0 km 2: Mayor–commission City 1831 54 Apopka: Orange: 54,873 34.6 sq mi 89.5 km 2: Mayor–commission City 1882 187 Arcadia† DeSoto ...