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In the pharmaceutical industry, drug dissolution testing is routinely used to provide critical in vitro drug release information for both quality control purposes, i.e., to assess batch-to-batch consistency of solid oral dosage forms such as tablets, and drug development, i.e., to predict in vivo drug release profiles. [1]
There must be phosphorus in the soil, but the plant must also absorb the phosphorus. Phosphorus uptake is limited by the chemical form of the phosphorus. A large portion of phosphorus in soil is in chemical compounds that plants can't absorb. [9] Phosphorus must be present in soil in specific chemical arrangements to be usable as plant nutrients.
Due to relatively high concentrations in the aqueous stock solutions (cf. Tables 1 and 2) the Hoagland solution is very good for the growth of plants with lower nutrient demands as well, such as lettuce and aquatic plants, with the further dilution of the preparation to 1 ⁄ 4 or 1 ⁄ 5 of the modified solution. [14]
Leaching can occur naturally seen from plant substances (inorganic and organic), [2] [3] solute leaching in soil, [4] and in the decomposition of organic materials. [5] Leaching can also be applied affectedly to enhance water quality and contaminant removal, [ 1 ] [ 6 ] as well as for disposal of hazardous waste products such as fly ash , [ 7 ...
A tablet is usually a compressed preparation that contains: 5-10% of the drug (active substance); 80% of fillers, disintegrants, lubricants, glidants, and binders; and; 10% of compounds which ensure easy disintegration, disaggregation, and dissolution of the tablet in the stomach or the intestine.
Friability and abrasion testing is performed in rotating testing drums, designed according to the pharmacopeia. The measured parameter is weight loss before and after testing and tumbling the tablets at a particular time and speed. In the friability test drum tablets are being carried up by a "shovel" and dropped.
Currently, the main purpose in managing soil phosphorus is to optimize crop production and minimize P loss from soils. PSB have attracted the attention of agriculturists as soil inoculums to improve the plant growth and yield. When PSB is used with rock phosphate, it can save about 50% of the crop requirement of phosphatic fertilizer.
In pharmaceutics, sink condition is a term mostly related to the dissolution testing procedure.. It means using a sheer volume of solvent, usually about 5 to 10 times greater than the volume present in the saturated solution of the targeted chemical (often the API, and sometimes the excipients) contained in the dosage form being tested.