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Tripe palms, also known as acanthosis palmaris, is a medical sign characterized by thick ridged velvety palms, typically as part of a paraneoplastic syndrome. [1] It resembles the lining of the stomach of some animals ( tripe ). [ 2 ]
FCP is sometimes seen together with other signs of internal cancer, especially malignant acanthosis nigricans, tripe palms, Leser–Trélat sign, and hypertrichosis lanuginosa acquisita. FCP tends to improve in association with surgical or chemotherapeutic therapy of the underlying internal cancer.
In some cases, paraneoplastic acanthosis nigricans (35% of patients), florid cutaneous papillomatosis, ichthyosis acquisita (acquired hypertrichosis lanuginosa), Cowden syndrome, tylosis, acrokeratosis paraneoplastica of Bazex or tripe palms accompany the sign of Leser–Trélat.
Acanthosis nigricans is a medical sign characterised by brown-to-black, poorly defined, velvety hyperpigmentation of the skin. [1] It is usually found in body folds, [2] such as the posterior and lateral folds of the neck, the armpits, groin, navel, forehead and other areas.
Respiratory symptoms occur in about 40% of people with dermatomyositis, and in these people, the symptoms may slowly progress and frequently are identified as an eventual cause of death. The main driver of respiratory failure in most of these patients is the damage to the lung interstitia , rather than diaphragm weakness.
Image credits: historycoolkids #3. Ronald (left) and Carl McNair (right) were born 10 months apart in the Segregated South. The two were inseparable as toddlers and well into adulthood.
The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. [3] Within the latter type, the hairs occur in structures called pilosebaceous units , each with hair follicle , sebaceous gland , and associated arrector pili muscle. [ 4 ]
An estimated 10% of people with yaws formerly were thought to develop tertiary disease symptoms, but more recently, tertiary yaws has been less frequently reported. [12] [2] Tertiary yaws can include gummatous nodules. It most commonly affects the skin. The skin of the palms and soles may thicken (hyperkeratosis).