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  2. Alpha-thalassemia - Wikipedia

    en.wikipedia.org/wiki/Alpha-thalassemia

    Alpha-thalassemia (α-thalassemia, α-thalassaemia) is an inherited blood disorder and a form of thalassemia. ... Silent carrier No symptoms 2 Alpha thalassemia trait

  3. Hemoglobin Barts - Wikipedia

    en.wikipedia.org/wiki/Hemoglobin_Barts

    If hemoglobin Barts is detected on a newborn screen, the patient is usually referred for further evaluation since detection of hemoglobin Barts can indicate either one alpha globin gene deletion, making the baby a silent alpha thalassemia carrier, two alpha globin gene deletions (alpha thalassemia), or hemoglobin H disease (three alpha globin ...

  4. Thalassemia - Wikipedia

    en.wikipedia.org/wiki/Thalassemia

    Severity of alpha thalassemia # of faulty alleles Types of alpha thalassemia [49] [50] Symptoms 1 Silent carrier No symptoms 2 Alpha thalassemia trait Minor anemia 3 Hemoglobin H disease Mild to moderate anemia; may lead normal life 4 Hemoglobin Bart’s hydrops fetalis Death usually occurs in utero or at birth

  5. Hemoglobin A - Wikipedia

    en.wikipedia.org/wiki/Hemoglobin_A

    Alpha-thalassemia (α-thalassemia) is defined by a lack of α-globin chain production in hemoglobin, and those who carry a mutation impacting the α-globin chain on only one chromosome are considered to have a “silent” α-thalassemia whereas, if the mutation is on both then it is considered an α-thalassemia trait.

  6. Hemoglobin variants - Wikipedia

    en.wikipedia.org/wiki/Hemoglobin_variants

    Mutations can caused impaired production of hemoglobin (thalassemia) or produce structurally altered hemoglobins. Some hemoglobin variants, such as HbS which causes sickle-cell anemia , are responsible for severe diseases and are considered hemoglobinopathies .

  7. List of hematologic conditions - Wikipedia

    en.wikipedia.org/wiki/List_of_hematologic_conditions

    Alpha-thalassemia: D56.0: 448, 33334, 33678: Alpha-thalassemia (α-thalassemia) is a form of thalassemia involving the genes HBA1 [20] and HBA2. [21] It is condition that causes a reduction of hemoglobin production. There are two types of Alpha-thalassemia, named hemoglobin Bart hydrops fetalis syndrome (also known as Hb Bart syndrome) and HbH ...

  8. Hemoglobin H disease - Wikipedia

    en.wikipedia.org/wiki/Hemoglobin_H_disease

    Hemoglobin H disease, also called alpha-thalassemia intermedia, is a disease affecting hemoglobin, the oxygen carrying molecule within red blood cells. It is a form of Alpha-thalassemia which most commonly occurs due to deletion of 3 out of 4 of the α-globin genes. [1]

  9. Hemoglobinopathy - Wikipedia

    en.wikipedia.org/wiki/Hemoglobinopathy

    Thalassemia subtypes of clinical significance are alpha thalassemia and beta thalassemia. A third subtype, delta thalassemia, affects production of HBA2 and is generally asymptomatic. [26] The severity of alpha thalassemia depends on how many of the four genes that code for alpha globin are faulty.

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