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The CRC Handbook of Chemistry and Physics is a comprehensive one-volume reference resource for science research. First published in 1914, it is currently (as of 2024) in its 105th edition, published in 2024. It is known colloquially among chemists as the "Rubber Bible", as CRC originally stood for "Chemical Rubber Company". [2]
Hazardous chemicals present physical and/or health threats to workers in clinical, industrial, and academic laboratories. Laboratory chemicals include cancer-causing agents (carcinogens), toxins (e.g., those affecting the liver, kidney, and nervous system), irritants, corrosives, sensitizers, as well as agents that act on the blood system or damage the lungs, skin, eyes, or mucous membranes.
The CRC Press was founded as the Chemical Rubber Company (CRC) in 1903 by brothers Arthur, Leo and Emanuel Friedman in Cleveland, Ohio, based on an earlier enterprise by Arthur, who had begun selling rubber laboratory aprons in 1900. [2] [3] The company gradually expanded to include sales of laboratory equipment to chemists.
Air flow in fume hood demonstrated by dry ice fog. A fume hood is typically a large piece of equipment enclosing six sides of a work area (including a movable sash window or door), the bottom of which is most commonly located at a standing work height (at least 28 to 34 inches (71 to 86 cm) above the floor).
Bretherick’s Handbook of Reactive Chemical Hazards is a well-established source of information on chemical safety, often known by its author’s name, and often cited in the chemical and chemical engineering literature. In recent editions it has been in two volumes, volume 1 being individual compounds and hazardous reactions, volume 2 being ...
Primary containment requires using proper storage containers, good microbiological technique, and the use of appropriate safety equipment such as biological safety cabinets. Secondary containment is the protection of the environment external to the laboratory from exposure to infectious materials and is provided by a combination of facility ...
The handbook was originally published in 1928 by the Chemical Rubber Company (now CRC Press) as a supplement (Mathematical Tables) to the CRC Handbook of Chemistry and Physics. Beginning with the 10th edition (1956), it was published as CRC Standard Mathematical Tables and kept this title up to the 29th edition (1991).
The FDA requires nonclinical laboratory studies on new drugs, food additives, and chemicals to assess their safety and potential effectiveness in humans in compliance with 21 CFR Part 58, Good Laboratory Practice for Nonclinical Studies under the Federal Food Drug and Cosmetic Act and Public Health Service Act. [16]