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Some clinicians believe that a reservoir of H. pylori in dental plaque can affect the result. [7] The test is especially done accompanying an eradication therapy by antibiotics (to avoid overdosing) or to check the success of an ulcer operation. In both cases, immunological tests can give false positive results. [1] [2]
Rapid urease test, also known as the CLO test (Campylobacter-like organism test), is a rapid diagnostic test for diagnosis of Helicobacter pylori. [1] The basis of the test is the ability of H. pylori to secrete the urease enzyme, which catalyzes the conversion of urea to ammonia and carbon dioxide .
Gastritis caused by H. pylori infection is termed Helicobacter pylori induced gastritis, and listed as a disease in ICD11. [6] [7] More than 80% of individuals infected with the bacterium are asymptomatic and it has been postulated that it may play an important role in the natural stomach ecology. [17]
H. pylori serologic testing, including IgG antibodies, are not recommended as a test of eradication as they may remain elevated for years after successful treatment of infection. [135] An endoscopic biopsy is an invasive means to test for H. pylori infection. Low-level infections can be missed by biopsy, so multiple samples are recommended.
A diagnosis for indigestion is based on symptoms, with a possible need for more diagnostic tests. In younger patients (less than 60 years of age) without red flags (e.g., weight loss), it is recommended to test for H. pylori noninvasively, followed by treatment with antibiotics in those who test positively.
SPOILERS BELOW—do not scroll any further if you don't want the answer revealed. The New York Times Today's Wordle Answer for #1264 on Wednesday, December 4, 2024
It can be caused by persistent infection with Helicobacter pylori, or can be autoimmune in origin. Those with autoimmune atrophic gastritis ( Type A gastritis ) are statistically more likely to develop gastric carcinoma , Hashimoto's thyroiditis , and achlorhydria .
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