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2. Linaclotide - Wikipedia

   en.wikipedia.org/wiki/Linaclotide

   Linaclotide, (sold under the brand name Linzess in the US and Mexico, and as Constella elsewhere) [6] is a drug used to treat irritable bowel syndrome with constipation and chronic constipation with no known cause.

3. Can Allergan's Key Drugs, Solid Pipeline Abate Generic Woes?

   www.aol.com/news/allergan-apos-key-drugs-solid...

   Allergan (AGN) is facing loss of exclusivity for many blockbuster products. However, drugs like Botox/Linzess, new drugs and cost cuts can shield it from potential sales drop.

4. Plecanatide - Wikipedia

   en.wikipedia.org/wiki/Plecanatide

   Minimal amounts of the drug are expected to be transported in to the body, and concentrations of plecanatide and its metabolites are undetectable in plasma following the recommended dosage of 3 mg. [12] [13] It has also been shown that dosages up to 48.6 mg produced no detectable concentration of plecanatide in human plasma at any time point ...

5. Bioequivalence - Wikipedia

   en.wikipedia.org/wiki/Bioequivalence

   In determining bioequivalence between two products such as a commercially available Branded product and a potential to-be-marketed Generic product, pharmacokinetic studies are conducted whereby each of the preparations are administered in a cross-over study (sometimes parallel study, when a cross-over study is not feasible) to volunteer subjects, generally healthy individuals but occasionally ...

6. Analysis-Ozempic on Wall Street's list for 2027 Medicare drug ...

   www.aol.com/news/analysis-ozempic-wall-streets...

   Medicare spent over $4.6 billion on the drug in 2022. Bristol Myers' Pomalyst and two other Abbvie drugs, Vraylar and Venclexta, may also be up for negotiation in 2027, analysts said.

7. Converting the Dissatisfied - AOL

   www.aol.com/news/2012-08-31-converting-the...

   The PDUFA date for the drug wasn't Yesterday, the biotech announced that the FDA had approved Linzess, its treatment for irritable bowel syndrome. Converting the Dissatisfied

8. Generic drug - Wikipedia

   en.wikipedia.org/wiki/Generic_drug

   A generic drug is a pharmaceutical drug that contains the same chemical substance as a drug that was originally protected by chemical patents. Generic drugs are allowed for sale after the patents on the original drugs expire.

9. Ironwood Pharmaceuticals Provides Fourth Quarter 2012 ... - AOL

   www.aol.com/news/2013-01-15-ironwood...

   Ironwood Pharmaceuticals Provides Fourth Quarter 2012 Investor Update Initiated Promotional Efforts for LINZESS™ (linaclotide) with Forest in December 2012; LINZESS Available to Patients in ...