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  2. Cortico-basal ganglia-thalamo-cortical loop - Wikipedia

    en.wikipedia.org/wiki/Cortico-basal_ganglia-th...

    The parallel CBGTC loops have been segregated according to the functions of associated cortical regions. One scheme involves the division into limbic and motor loops, with the motor loops containing indirect and direct pathways, which are in turn interconnected with the limbic loop that projects into the ventral striatum. [9]

  3. Indirect pathway - Wikipedia

    en.wikipedia.org/wiki/Indirect_pathway

    The indirect pathway, sometimes known as the indirect pathway of movement, is a neuronal circuit through the basal ganglia and several associated nuclei within the central nervous system (CNS) which helps to prevent unwanted muscle contractions from competing with voluntary movements. [1] It operates in conjunction with the direct pathway.

  4. Direct pathway - Wikipedia

    en.wikipedia.org/wiki/Direct_pathway

    The direct pathway, sometimes known as the direct pathway of movement, is a neural pathway within the central nervous system (CNS) through the basal ganglia which facilitates the initiation and execution of voluntary movement. [1] It works in conjunction with the indirect pathway.

  5. Basal ganglia disease - Wikipedia

    en.wikipedia.org/wiki/Basal_ganglia_disease

    The indirect pathway is responsible for the termination of movement. The indirect pathway inhibits unwanted movements by simultaneous increase in excitatory input to other GPi and SNr neurons. [4] Similar to the direct pathway, the indirect pathway is regulated by striatal dopamine. D 2 dopamine receptors inhibit transmission via the indirect ...

  6. Medium spiny neuron - Wikipedia

    en.wikipedia.org/wiki/Medium_spiny_neuron

    The balance of direct/indirect activity in movement is supported by evidence from neurodegenerative disorders, including Parkinson's disease (PD), which is characterized by loss of dopamine neurons projecting to the striatum, hypoactivity in direct pathway and hyperactivity in indirect pathway neurons, along with motor dysfunction. [21]

  7. Trump vows to pardon Jan. 6 defendants on 'Day One.' Are ...

    www.aol.com/trump-vows-pardon-jan-6-220442104.html

    In his first sit-down broadcast interview since the Nov. 5 election, President-elect Donald Trump said he would begin pardoning rioters who participated in the Jan. 6 attack on the U.S. Capitol on ...

  8. Nigrostriatal pathway - Wikipedia

    en.wikipedia.org/wiki/Nigrostriatal_pathway

    The substantia nigra is located in the ventral midbrain of each hemisphere. It has two distinct parts, the pars compacta (SNc) and the pars reticulata (SNr). The pars compacta contains dopaminergic neurons from the A9 cell group that forms the nigrostriatal pathway that, by supplying dopamine to the striatum, relays information to the basal ganglia.

  9. Pregnant Woman Reportedly Stabbed 14 Times by Pizza Delivery ...

    www.aol.com/pregnant-woman-reportedly-stabbed-14...

    The incident happened on Sunday, Dec. 22, 2024, at the Riviera Motel in Kissimmee, Florida according to the Osceola County Sheriff’s Office Pregnant Woman Reportedly Stabbed 14 Times by Pizza ...