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Lipedema is a condition that is almost exclusively found in women [3] and results in enlargement of both legs due to deposits of fat under the skin. [2] Women of any weight may be affected [ 2 ] [ 3 ] and the fat is resistant to traditional weight-loss methods. [ 4 ]
[1] [2] Lower legs and heels may also be involved, however the distal parts of feet and toes are usually spared. Patients may also experience high-graded fever, pitting edema and hypotension. The clinical presentation usually resembles cellulitis, however bilateral involvement is a differentiating feature.
Lymphedema can be present at birth, develop at the onset of puberty (praecox), or not become apparent for many years into adulthood (tarda). In men, lower-limb primary lymphedema is most common, occurring in one or both legs. Some cases of lymphedema may be associated with other vascular abnormalities. [4] [citation needed]
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After losing 350 pounds, Jaqueline Adan's legs looked so big, felt painful. Doctors dismissed her. Told her to lose weight. She has lipedema that was missed.
She has lipedema, a fat storage disorder. She is undergoing surgery to help ‘My legs were always just big’: Dancer details living with lipedema, having surgery to treat it
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Milroy's disease is also known as primary or hereditary lymphedema type 1A or early onset lymphedema. It is a very rare disease with only about 200 cases reported in the medical literature. Milroy's disease is an autosomal dominant condition caused by a mutation in the FLT4 gene which encodes the vascular endothelial growth factor receptor 3 ...
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