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Although meningitis is a notifiable disease in many countries, the exact incidence rate is unknown. [22] In 2013 meningitis resulted in 303,000 deaths – down from 464,000 deaths in 1990. [86] In 2010 it was estimated that meningitis resulted in 420,000 deaths, [87] excluding cryptococcal meningitis. [42]
Meningococcal meningitis is a form of bacterial meningitis. Meningitis is a disease caused by inflammation and irritation of the meninges, the membranes surrounding the brain and spinal cord. In meningococcal meningitis this is caused by the bacteria invading the cerebrospinal fluid and circulating through the central nervous system. Sub ...
Meningococcal vaccine refers to any vaccine used to prevent infection by Neisseria meningitidis. [9] Different versions are effective against some or all of the following types of meningococcus: A, B, C, W-135, and Y. [9] [10] The vaccines are between 85 and 100% effective for at least two years. [9]
The symptoms are caused by the bacteria entering the lining of the brain and the spinal cord, causing the lining to swell and increase pressure, the CDC says. In extreme cases of meningitis or if ...
Some of the possible symptoms of chronic meningitis (due to any cause) include headache, nausea and vomiting, fever, and visual impairment. Nuchal rigidity (or neck stiffness with discomfort in trying to move the neck), a classic symptom in acute meningitis, was seen in only 45% of cases of chronic meningitis with the sign being even more rare in non-infectious causes.
Most forms of aseptic meningitis are viral in origin, though neoplastic and Lyme disease meningitis are also aseptic. California encephalitis virus; Central nervous system viral disease; Cytomegalovirus encephalitis; SARS-CoV-2; Eastern equine encephalitis; Enterovirus encephalitis; Epstein Barr Virus encephalitis; Herpes simplex encephalitis ...
NmVac4-A/C/Y/W-135 is the commercial name for a polysaccharide vaccine that protects against meningococcal meningitis caused by Neisseria meningitidis, specifically the serotypes A, C, Y, and W-135. This vaccine is part of a broader group of meningococcal vaccines .
Penbraya is a pentavalent conjugate vaccine developed by Pfizer for the prevention of invasive meningococcal disease in people 10 through 25 years of age. [4] Invasive meningococcal disease, caused by the bacterium Neisseria meningitidis, can lead to serious conditions such as meningitis (inflammation of the brain and spinal cord lining) and sepsis. [5]
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