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Potassium binders are medications that bind potassium ions in the gastrointestinal tract, thereby preventing its intestinal absorption. This category formerly consisted solely of polystyrene sulfonate, a polyanionic resin attached to a cation, administered either orally or by retention enema to patients who are at risk of developing hyperkalaemia (abnormal high serum potassium levels).
These polymers are derived from polystyrene by the addition of sulfonate functional groups. Sodium polystyrene sulfonate was approved for medical use in the United States in 1958. [1] A polystyrene sulfonate was developed in the 2000s to treat Clostridioides difficile associated diarrhea under the name Tolevamer, [2] but it was never marketed.
Ion-exchange resin beads. An ion-exchange resin or ion-exchange polymer is a resin or polymer that acts as a medium for ion exchange, that is also known as an ionex. [1] It is an insoluble matrix (or support structure) normally in the form of small (0.25–1.43 mm radius) microbeads, usually white or yellowish, fabricated from an organic polymer substrate.
Tolevamer was designed to bind the enterotoxins of Clostridioides difficile.Since it has no antibiotic properties, it does not harm the gut flora.Early studies used the sodium salt, but it was soon replaced with the potassium sodium salt to prevent hypokalaemia, which is often associated with diarrhea.
Colestilan (INN, trade name BindRen) is a medication that acts as a phosphate binder [1] and bile acid sequestrant. [2] It is an ion-exchange resin, is an orally administered bile acid sequestrant that is being developed by Mitsubishi Tanabe Pharma Corporation for the treatment of hypercholesterolaemia and hyperphosphataemia.
The Bahamas has “firmly rejected” President-election Donald Trump's proposal to fly deported immigrants out of the U.S. and into the small island nation about 100 miles southeast of Florida ...
The main component of both products is anhydrous sodium sulfate. Contains a small amount of polyethylene glycol. Whole bowel irrigation ( WBI ) is a medical process involving the rapid administration of large volumes of an osmotically balanced macrogol solution ( GoLYTELY , CoLyte ), either orally or via a nasogastric tube , to flush out the ...
AAPL Market Cap data by YCharts. Other noteworthy examples include selling out of oil and gas stocks during the downturn of 2020. In the last four years, the energy sector is up 129%.
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