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Cutaneous squamous-cell carcinoma (cSCC), also known as squamous-cell carcinoma of the skin or squamous-cell skin cancer, is one of the three principal types of skin cancer, alongside basal-cell carcinoma and melanoma. [10] cSCC typically presents as a hard lump with a scaly surface, though it may also present as an ulcer. [1]
Squamous-cell carcinoma (SCC), also known as epidermoid carcinoma, comprises a number of different types of cancer that begin in squamous cells. [1] These cells form on the surface of the skin, on the lining of hollow organs in the body, and on the lining of the respiratory and digestive tracts .
Epidermal inclusion cysts account for approximately 85–95% of all excised cysts; malignant transformation is exceedingly rare. The incidence of squamous cell carcinoma developing from an epidermal inclusion cyst has been estimated to range from 0.011 to 0.045%. [5]
The lesion at the base of the keratin mound is benign in the majority of cases. Malignancy is present in up to 20% of cases, with squamous-cell carcinoma being the most common type. The incidence of squamous-cell carcinoma increases to 37% when the cutaneous horn is present on the penis. [3] Cutaneous horn in right ear
Oropharyngeal cancer, [1] [2] [3] also known as oropharyngeal squamous cell carcinoma and tonsil cancer, [1] is a disease in which abnormal cells with the potential to both grow locally and spread to other parts of the body are found in the oral cavity, in the tissue of the part of the throat that includes the base of the tongue, the tonsils, the soft palate, and the walls of the pharynx.
The World Health Organization (WHO) has identified three subtypes of nasopharyngeal carcinoma: [citation needed] type 1: squamous cell carcinoma, typically found in older adults; type 2: non-keratinizing carcinoma; type 3: undifferentiated carcinoma; Type 3 is most commonly found among younger children and adolescents, with a few type 2 cases.
Squamous cell carcinoma is most likely to appear in males over 40 years of age with a history of heavy alcohol use coupled with smoking. [citation needed] All squamous cell carcinomas arising from the oropharynx, and all neck node metastases of unknown primary should undergo testing for HPV status. This is essential to adequately stage the ...
It is typically a squamous-cell carcinoma, reflecting its origin from the epithelium of the larynx. The prognosis is affected by the location of the tumour. For the purposes of staging , the larynx is divided into three anatomical regions: the glottis (true vocal cords , anterior and posterior commissures); the supraglottis ( epiglottis ...