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The urachus forms from the distal end of the allantois in the embryo, and develops into a closed cord between the base of the bladder, and the navel. [1] It drains the bladder of the fetus that joins and runs within the umbilical cord . [ 2 ]
4. Urinary bladder. 5. Urachus. cl. Cloaca. cp. Elevation which becomes clitoris or penis. i. Lower part of the intestine. ls. Fold of integument from which the labia majora or scrotum are formed. m, m. Right and left Müllerian ducts uniting together and running with the Wolffian ducts in gc, the genital cord. ot.
A urachal fistula is a congenital disorder caused by the persistence of the allantois (later, urachus), the structure that connects an embryo's bladder to the yolk sac. Normally, the urachus closes off to become the median umbilical ligament; however, if it remains open, urine can drain from the bladder to an opening by the umbilicus. [1]
During fetal development, the allantois becomes the urachus, a duct between the bladder and the yolk sac. A patent allantois can result in a urachal cyst. Because the allantois can be cultured ex vivo, it has utility as a model system for studying the formation of blood vessels as well as considerable usefulness in drug screening.
If the urachus fails to close during fetal life, it can result in anatomical abnormalities such as a urachal cyst, urachal fistula, urachal diverticulum or urachal sinus. In very rare cases the urachus can fail to close fully. This can lead to a condition known as a patent urachus (also urachal fistula). Although it is mainly immediately ...
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Urinary bladder: Urinary bladder: Urinary bladder: 5. Urachus: Urachus: Urachus: i. Lower part of the intestine: i. Lower part of the intestine: i. Lower part of the intestine: cl. Cloaca: cp. Elevation which becomes clitoris or penis (genital tubercle) cc. Corpus cavernosum clitoridis: cp. Corpus cavernosum penis cut short ug. Sinus urogenitalis
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