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The urachus is also subject to neoplasia. Urachal adenocarcinoma is histologically similar to adenocarcinoma of the bowel. Rarely, urachus carcinomas can metastasise to other regions of the body, including pelvic bones and the lung. [7] One urachal mass has been reported that was found to be a manifestation of IgG4-related disease. [8]
4. Urinary bladder. 5. Urachus. cl. Cloaca. cp. Elevation which becomes clitoris or penis. i. Lower part of the intestine. ls. Fold of integument from which the labia majora or scrotum are formed. m, m. Right and left Müllerian ducts uniting together and running with the Wolffian ducts in gc, the genital cord. ot.
If the urachus fails to close during fetal life, it can result in anatomical abnormalities such as a urachal cyst, urachal fistula, urachal diverticulum or urachal sinus. In very rare cases the urachus can fail to close fully. This can lead to a condition known as a patent urachus (also urachal fistula). Although it is mainly immediately ...
During fetal development, the allantois becomes the urachus, a duct between the bladder and the yolk sac. A patent allantois can result in a urachal cyst. Because the allantois can be cultured ex vivo, it has utility as a model system for studying the formation of blood vessels as well as considerable usefulness in drug screening. [9]
4. Urinary bladder. 5. Urachus. cl. Cloaca. cp. Elevation which becomes clitoris or penis. i. Lower part of the intestine. ls. Fold of integument from which the labia majora or scrotum are formed. m, m. Right and left Müllerian ducts uniting together and running with the Wolffian ducts in gc, the genital cord. ot.
A urachal fistula is a congenital disorder caused by the persistence of the allantois (later, urachus), the structure that connects an embryo's bladder to the yolk sac. Normally, the urachus closes off to become the median umbilical ligament ; however, if it remains open, urine can drain from the bladder to an opening by the umbilicus .
The embryonic allantois becomes the fetal urachus, which connects the fetal bladder (developed from cloaca) to the yolk sac. The urachus removes nitrogenous waste from the fetal bladder. [13] After birth the urachus is closed, and becomes the median umbilical ligament.
Urinary bladder: Urinary bladder: Urinary bladder: 5. Urachus: Urachus: Urachus: i. Lower part of the intestine: i. Lower part of the intestine: i. Lower part of the intestine: cl. Cloaca: cp. Elevation which becomes clitoris or penis (genital tubercle) cc. Corpus cavernosum clitoridis: cp. Corpus cavernosum penis cut short ug. Sinus urogenitalis