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  2. Pfizer's twice-daily weight-loss pill discontinued due to ...

    www.aol.com/ozempic-without-injection-weight...

    Pfizer announced on Dec. 1 that it was discontinuing phase 3 clinical trials of the twice-daily version due to high rates of adverse side effects. While these were mostly mild, a large percentage ...

  3. Pfizer drops twice-daily version of obesity pill over side ...

    www.aol.com/news/pfizer-pulls-plug-twice-daily...

    That compares with 15% for Eli Lilly's experimental oral drug at 36 weeks at a high dose. Pfizer characterized the side effects in the twice-daily version study as mild, but the rates were high ...

  4. Pfizer moves forward with once-daily weight-loss pill - AOL

    www.aol.com/news/pfizer-moves-forward-once-daily...

    (Reuters) -Pfizer plans to move a reworked, once-a-day version of its weight-loss pill danuglipron into clinical trials later this year, the company said on Thursday, after scrapping a twice ...

  5. Polypharmacy - Wikipedia

    en.wikipedia.org/wiki/Polypharmacy

    Every medication has potential adverse side-effects. With every drug added, there is an additive risk of side-effects. Also, some medications have interactions with other substances, including foods, other medications, and herbal supplements. [46] 15% of older adults are potentially at risk for a major drug-drug interaction. [47]

  6. Santonin - Wikipedia

    en.wikipedia.org/wiki/Santonin

    (This was a total dose; many regimens called for three doses daily over three days, and the "three teaspoons three times a day for three days" regimen was typical around the 1950s when use of santonin was starting to wane; actual doses per dose were closer to 20–30 milligrams per adult dose in a typical "'50s regimen", but "one-shot" doses of ...

  7. Valdecoxib - Wikipedia

    en.wikipedia.org/wiki/Valdecoxib

    Other reported side effects were angina and Stevens–Johnson syndrome. Pfizer first acknowledged cardiovascular risks associated with Bextra in October 2004. The American Heart Association soon after was presented with a report indicating patients using Bextra while recovering from heart surgery were 2.19 times more likely to suffer a stroke ...

  8. Pfizer moving ahead with plans for once-daily weight loss pill

    www.aol.com/pfizer-moving-ahead-plans-once...

    Dose optimization studies are planned. Pfizer had been looking into a… The pharmaceutical giant said clinical evaluation of once-daily doses of its oral GLP-1 agonist candidate danuglipron ...

  9. Pfizer moving forward with once-daily weight-loss pill seen ...

    www.aol.com/pfizer-moving-forward-once-daily...

    Pfizer hasn't yet tapped into the highly lucrative market of diabetes drugs that have recently been increasingly used for weight loss purposes. Pfizer moving forward with once-daily weight-loss ...

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