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Narcolepsy is a chronic neurological disorder that impairs the ability to regulate sleep–wake cycles, and specifically impacts REM (rapid eye movement) sleep. [1] The pentad symptoms of narcolepsy include excessive daytime sleepiness (EDS), sleep-related hallucinations, sleep paralysis, disturbed nocturnal sleep (DNS), and cataplexy. [1]
This condition was first discovered in 1995 by Melberg et al. when they described 5 members of a 4-generation Swedish family where cerebellar ataxia and sensorineural deafness presented as an autosomal dominant trait, 4 of them had narcolepsy and 2 had diabetes mellitus. The oldest members had psychiatric symptoms, neurological anomalies, and ...
Narcoleap is a Canadian web series created by Kate Green. [1] The series stars Chelsey Reist, Madison Smith, Austin Eckhert, Nicole Oliver, Aleks Paunovic, Cameron Bancroft, and Nhi Do, and is loosely based on the original concept by Donald Auger. [2]
Naan Sigappu Manithan (transl. I am a Red Man) is a 2014 Tamil-language action thriller film [1] directed by Thiru and produced by UTV Motion Pictures.Co-produced by Vishal, the film stars himself in the leading role with Lakshmi Menon and Ineya in supporting roles, while G. V. Prakash Kumar composed the film's music.
This page was last edited on 26 November 2022, at 01:51 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
Firazorexton was studied by Takeda for the treatment of narcolepsy. [3] [4] [5] It is a small-molecule and orally active compound and acts as a highly selective agonist of the orexin receptor 2 (OX 2) with >700-fold selectivity over the orexin receptor 1 (OX 1). [3] [4] [6] [7] Firazorexton is related to danavorexton (TAK-925). [8]
Methylphenidate, sold under the brand names Ritalin (/ ˈ r ɪ t ə l ɪ n / RIT-ə-lin) and Concerta (/ k ə n ˈ s ɜːr t ə / kən-SUR-tə) [citation needed] among others, is a central nervous system (CNS) stimulant indicated in the pharmacotherapy of attention deficit hyperactivity disorder (ADHD) and narcolepsy.
Amphetamine [note 2] (contracted from alpha-methylphenethylamine) is a central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity; it is also used to treat binge eating disorder in the form of its inactive prodrug lisdexamfetamine.
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