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Asunercept (INN; development codes APG101 and CAN008) [1] is a soluble CD95-Fc fusion protein which is in clinical development for the treatment of glioblastoma multiforme (GBM) and myelodysplastic syndromes (MDS). [2] Asunercept has been granted orphan drug status for the treatment of GBM and MDS in the EU and the US.
New data shows that more than half (58 per cent) of those people diagnosed with lung, liver, brain, oesophagus, pancreas or stomach cancer will die from their disease within 12 months, and they ...
John McCain suffers from a highly malignant form of cancer that spreads quickly due to its association with a large network of blood vessels in the brain. What is glioblastoma? McCain’s brain ...
The purpose of the ReSPECT-GBM Clinical Trial is to assess the safety, tolerability, and distribution of a new medication, Rhenium (186Re) Obisbemeda, in adults with recurrent glioblastoma after standard surgical, radiation, and/or chemotherapy treatment. ReSPECT-GBM is supported by the U.S. National Institutes of Health / National Cancer ...
Bestselling author Sophie Kinsella revealed Wednesday that she was diagnosed with brain cancer in 2022 and since then has undergone surgery, radiation and chemotherapy to treat the aggressive disease.
The American National Comprehensive Cancer Network's official guidelines list TTFields as an option for the treatment of recurrent glioblastoma, but note substantial disagreement among the members of the expert panel making this recommendation. [2] High-quality evidence for the efficacy of TTFields in oncology is limited.
Bevacizumab, sold under the brand name Avastin among others, is a monoclonal antibody medication used to treat a number of types of cancers and a specific eye disease. [30] [28] For cancer, it is given by slow injection into a vein (intravenous) and used for colon cancer, lung cancer, ovarian cancer, glioblastoma, hepatocellular carcinoma, and renal-cell carcinoma. [31]
Glioblastoma pre (left) and post (right) resection. Surgery is the first stage of treatment of glioblastoma. An average GBM tumor contains 10 11 cells, which is on average reduced to 10 9 cells after surgery (a reduction of 99%). Benefits of surgery include resection for a pathological diagnosis, alleviation of symptoms related to mass effect ...