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Robenacoxib, sold under the brand name Onsior, is a nonsteroidal anti-inflammatory drug (NSAID) used in veterinary medicine for the relief of pain and inflammation in cats and dogs. [ 4 ] [ 5 ] It is a COX-2 inhibitor ( coxib ).
Polysulfated glycosaminoglycan (PSGAG), sold under the brand name Adequan, is an injectable drug for dogs and horses that is used to alleviate the limpness, pain, and lowered range of motion caused by arthritis. [2]
Deslorelin is used in veterinary medicine.One commercial form of deslorelin acetate is marketed by Peptech with the brand name Ovuplant. [3] Another form is available in the United States, Sucromate Equine, [4] which was FDA-approved for use in horses in November 2010. [5]
pergolide – dopamine receptor agonist used for the treatment of pituitary pars intermedia dysfunction in horses; phenobarbital – anti-convulsant used for seizures; phenylbutazone – nonsteroidal anti-inflammatory drug (NSAID) phenylpropanolamine – controls urinary incontinence in dogs
In pharmacokinetics, the rate of infusion (or dosing rate) refers not just to the rate at which a drug is administered, but the desired rate at which a drug should be administered to achieve a steady state of a fixed dose which has been demonstrated to be therapeutically effective. Abbreviations include K in, [1] K 0, [2] or R 0.
In dogs, sheep, horses, and cattle, the half-life is very short: only 1.21– 5.97 minutes. Complete elimination of the drug can take up to 23 minutes in sheep and up to 49 minutes in horses. [1] [3] In young rats the half-life is one hour. [18] Xylazine has a large volume of distribution of V d = 1.9 – 2.5 for horses, cattle, sheep, and dogs ...
The drug possess a biological half-life of 14 days when administered by intramuscular injection. [1] Boldenone is a substrate for 5α-reductase and may be converted by this enzyme into 1-testosterone (δ 1 -dihydrotestosterone, δ 1 -DHT, dihydroboldenone) in tissues that express it such as the skin , hair follicles , and prostate gland . [ 6 ]
The drug appears to have been an early development project of Roussel Uclaf, a French pharmaceutical company, and by the early 1970s, it was being sold as an injectable. [18] There are a number of trenbolone esters but trenbolone acetate is the only one known to be produced in veterinary AAS manufacturers.