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The Food and Drug Administration recently cautioned consumers against using 27 different kinds of eyedrops — its third eyedrop-related warning this year — leading Americans to question whether ...
“Very few foreign drugmakers have been inspected in the past four years.” In 2022, FDA foreign inspections were down 79% from 2019, according to agency records collected by Ridley's group.
Three people have died, and four others have had their eyeballs removed because of rare bacterial infections linked to contaminated eyedrops, the Centers for Disease Control and Prevention ...
On February 2, 2023, the CDC advised people to stop using EzriCare Artificial Tears and said that the eye drops were contaminated. The P. aeruginosa strain had been found in 55 people across 12 states as of January 31, resulting in one death and vision loss in five people. A recall was ordered for EzriCare Artificial Tears, which later included ...
Figure 1.0 - Basic anatomical features of the human eye. Ophthalmic drug administration is the administration of a drug to the eyes, most typically as an eye drop formulation. Topical formulations are used to combat a multitude of diseased states of the eye. These states may include bacterial infections, eye injury, glaucoma, and dry eye. [1]
Chloroquine retinopathy is a form of toxic retinopathy (damage of the retina) caused by the drugs chloroquine or hydroxychloroquine, which are sometimes used in the treatment of autoimmune disorders such as rheumatoid arthritis and systemic lupus erythematosus. This eye toxicity limits long-term use of the drugs. [3]
The FDA recently cautioned against using dozens of kinds of eyedrops — its third warning this year — leading to some wondering whether any drops are safe to use. Eye doctors weigh in.
In one study, 10 people were given two drops of 0.5 mg/mL of tetryzoline eye drops (0.025–0.05 mg) at 0 hrs, 4 hrs, 8 hrs, and 12 hrs. Within a 24-hour time window, since the last dose of tetryzoline, the blood serum concentration of tetryzoline in the test subjects was 0.068-0.380 ng /mL and the urine concentration was 13–210 ng/mL.