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Multiple myeloma is usually diagnosed because malignant plasma cells continue to ... have a 10-year overall survival of 70% and a 6-year progression-free survival of ...
Since sirolimus is not administered until at least 3–12 months after transplant, these median survival estimates were conditional on surviving 1 year post-transplant. [33] As lung transplantation has improved since the late 20th century with advancements in perioperative management, surgical technique and postoperative rehabilitation, 5-year ...
MGUS is a relatively stable condition afflicting 3% of people aged 50 and 5% of people aged 70; it progresses to multiple myeloma at a rate of 0.5–1% cases per year; smoldering multiple myeloma does so at a rate of 10% per year for the first 5 years, but then falls off sharply to 3% per year for the next 5 years and thereafter to 1% per year.
Older age at diagnosis and treatment resulted in published reports of median survival of approximately 5 years from diagnosis. [4] Currently, median survival is 6.5 years. [ 77 ] In rare instances, Waldenström macroglobulinemia progresses to multiple myeloma .
[3] [65] [66] IPF progression is associated with an estimated median survival time of 2 to 5 years following diagnosis. [1] [3] The 5-year survival for IPF ranges between 20 and 40%, [66] a mortality rate higher than that of a number of malignancies, including colon cancer, multiple myeloma and bladder cancer. [65] [66]
At least one case of FIP1L1-PDGFRA fusion gene-induced eosinophilic leukemia presenting with myeloid sarcoma and eosinophilia has been reported. This form of myeloid sarcoma is distinguished by its highly successful treatment with imatinib (the recommended treatment for FIP1L1-PDGRGA fusion gene-induced eosinophilic leukemia) rather than more aggressive and toxic therapy.
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