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The rates of fat embolism in long bone fractures vary from 1% to 30%. The mortality rate of fat-embolism syndrome is approximately 10–20%. [ 7 ] However, fat globules have been detected in 67% of those with orthopaedic trauma and can reach as high as 95% if the blood is sampled near the fracture site.
Dysbaric osteonecrosis or DON is a form of avascular necrosis where there is death of a portion of the bone that is thought to be caused by nitrogen (N 2) embolism (blockage of the blood vessels by a bubble of nitrogen coming out of solution) in divers. [1] Although the definitive pathologic process is poorly understood, there are several ...
Fat embolism usually occurs when endogenous (from sources within the organism) fat tissue escapes into the blood circulation. The usual cause of fat embolism is therefore the fracture of tubular bones (such as the femur ), which will lead to the leakage of fat tissue within the bone marrow into ruptured vessels.
a history of long-term intravenous therapy [1] (for air embolism) Bone fracture (for fat embolism) [4] A septal defect of the heart makes it possible for paradoxical embolization, which happens when a clot in a vein enters the right side of the heart and passes through a hole into the left side. The clot can then move to an artery and cause ...
Trabecular bone (or cancellous bone) is the sponge-like bone in the ends of long bones and vertebrae. Cortical bone is the hard outer shell of bones and the middle of long bones. Because osteoblasts and osteoclasts inhabit the surface of bones, trabecular bone is more active and is more subject to bone turnover and remodeling.
Risk factors include bone fractures, joint dislocations, alcoholism, and the use of high-dose steroids. [1] The condition may also occur without any clear reason. [1] The most commonly affected bone is the femur (thigh bone). [1] Other relatively common sites include the upper arm bone, knee, shoulder, and ankle. [1]
An open fracture (or compound fracture) is a bone fracture where the broken bone breaks through the skin. [2] A bone fracture may be the result of high force impact or stress , or a minimal trauma injury as a result of certain medical conditions that weaken the bones, such as osteoporosis , osteopenia , bone cancer , or osteogenesis imperfecta ...
Heterotopic ossification of varying severity can be caused by surgery or trauma to the hips and legs. About every third patient who has total hip arthroplasty (joint replacement) or a severe fracture of the long bones of the lower leg will develop heterotopic ossification, but is uncommonly symptomatic.