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Spironolactone is a once-a-day tablet that can stop hair loss from progressing and encourage new hair growth. It’s especially useful for women with hormonal issues like PCOS. It may take six to ...
For example, if an excess of male hormones (androgens such as testosterone) is responsible for the hair loss, as it is with PCOS, a diuretic called spironolactone, which has anti-androgen effects ...
Spironolactone can be used in the treatment of female-pattern hair loss (pattern scalp hair loss in women). [68] There is tentative low quality evidence supporting its use for this indication. [69] Although apparently effective, not all cases of female-pattern hair loss are dependent on androgens. [70]
The primary characteristic of all forms of hypertrichosis is excessive hair. Hair in hypertrichosis is usually longer than expected [7] and may consist of any hair type (lanugo, vellus, or terminal). [18] Patterned forms of hypertrichosis cause hair growth in patterns. Generalized forms of hypertrichosis result in hair growth over the entire body.
The AR antagonism of spironolactone mostly underlies its antiandrogenic activity and is the major mechanism responsible for its therapeutic benefits in the treatment of androgen-dependent conditions like acne, hirsutism, and pattern hair loss and its usefulness in hormone therapy for transgender women.