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Testosterone is the primary male sex hormone and androgen in males. [3] In humans, testosterone plays a key role in the development of male reproductive tissues such as testicles and prostate, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of body hair.
The HPG axis plays a critical part in the development and regulation of a number of the body's systems, such as the reproductive and immune systems. Fluctuations in this axis cause changes in the hormones produced by each gland and have various local and systemic effects on the body. The axis controls development, reproduction, and aging in ...
However, when T levels are reduced through ADT, the body may compensate by increasing the production of P4, which can then serve as a substrate for the backdoor pathway. One of the main drawbacks of this increased production of P4 leads to an increase in DHT levels, which fuel the growth of prostate cancer cells.
Anti-Müllerian hormone (AMH) causes the paramesonephric ducts to regress. Testosterone, which is secreted and converts the mesonephric ducts into male accessory structures, such as epididymis, vas deferens and seminal vesicle. Testosterone will also control the descending of the testes from the abdomen into the scrotum.
Testosterone can be taken by a variety of different routes of administration. [2] [3] These include oral, buccal, sublingual, intranasal, transdermal (gels, creams, patches, solutions), vaginal (creams, gels, suppositories), rectal (suppositories), by intramuscular or subcutaneous injection (in oil solutions or aqueous suspensions), and as a subcutaneous implant.
Researchers say higher testosterone levels in men under age 65 who are overweight or have obesity can help lower the risk of developing type 2 diabetes
Recently, the subject of using testosterone as another way of managing symptoms, such as loss as sex drive, has come back into the news, as actress Kate Winslet has sung the hormone's praises.
A.—Diagram of the primitive urogenital organs, from 'Diagrams to show the development of male and female generative organs from a common type' * w, w. Right and left Wolffian ducts. The observable, visual differences become apparent between male or the female reproductive organs are not seen initially.