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Lipoic acid (LA), also known as α-lipoic acid, alpha-lipoic acid (ALA) and thioctic acid, is an organosulfur compound derived from caprylic acid (octanoic acid). [3] ALA, which is made in animals normally, is essential for aerobic metabolism. It is also available as a dietary supplement or pharmaceutical drug in some countries.
Alpha lipoic acid (ALA) with benfotiamine is a proposed pathogenic treatment for painful diabetic neuropathy only. [119] The results of two systematic reviews state that oral ALA produced no clinically significant benefit, intravenous ALA administered over three weeks may improve symptoms and that long-term treatment has not been investigated ...
Alpha-lipoic acid is an antioxidant that might improve insulin sensitivity and lower blood sugar. While this may be beneficial for those managing blood glucose naturally, it may create issues for ...
What causes sciatica and how can you ease the pain of this common condition? Here's what experts suggest. Skip to main content. Sign in. Mail. 24/7 Help. For premium support please call: 800-290 ...
Benfotiamine has been studied in laboratory models of diabetic retinopathy, neuropathy, and nephropathy. [10] A 2021 review of its use for diabetic polyneuropathy described two clinical trials which showed improvements in neuropathic pain and neuropathic symptoms scores, the latter of which showed a dose-response effect. [4]
What is the sciatic nerve? The sciatic nerve is about 2 centimeters in diameter and consists of the L4 to S2 nerve roots, which join at the pelvis and run down the back of the thigh, says Chellsen.
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